Tetradecane

Tetradecane

SCHEMBL476482

C=CCOS(=O)(=O)O.CCCCCCCCCCCCCC

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
ZDHHC20 Q5W0Z9 1/20 0.40
ZDHHC2 Q9UIJ5 1/20 0.40
CA1 P00915 11/20 0.39
CA2 P00918 11/20 0.39
CA9 Q16790 8/20 0.39
CA12 O43570 3/20 0.39
CA7 P43166 3/20 0.39
CA14 Q9ULX7 3/20 0.39
CA3 P07451 2/20 0.39
CA4 P22748 2/20 0.39
CA6 P23280 2/20 0.39
CA5A P35218 2/20 0.39
CA5B Q9Y2D0 2/20 0.39
HPGD P15428 2/20 0.38
RECQL P46063 2/20 0.38
GLA P06280 1/20 0.38
MAPK1 P28482 1/20 0.38
EPHX2 P34913 1/20 0.38
BLM P54132 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27463953 0.93 CA1 (0.47) TSHRCA1CA2CA9CA12
SCHEMBL6017176 0.91 TSHR (0.44) TSHRZDHHC20ZDHHC2CA1CA2
SCHEMBL1426857 0.91 CA1 (0.46) TSHRCA1CA2CA9CA12
Sulfuric Acid SCHEMBL28087109 0.90 TSHR (0.42) TSHRZDHHC20CA1CA2CA9
SCHEMBL2490189 0.89 TSHR (0.41) TSHRCA1CA2CA9CA12
Dodecanoate SCHEMBL29080295 0.88 GPR84 (0.53) TSHRRECQLBLM
SCHEMBL1426860 0.86 TSHR (0.65) TSHRCA1CA2CA9CA12
Alcohol SCHEMBL181400 0.85 TSHR (0.33) TSHRCA2CA9
SCHEMBL15349414 0.85 CA2 (0.36) TSHRCA1CA2CA9CA12
SCHEMBL29655 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2110121-B1 Cosmetic and dermatological compositions in particular for the treatment of keratin containing substrates STRAETMANS CHEMISCHE PRODUKTE GMBH DR (DE) 2012-02-01 EP disclosed
US-8057786-B2 Cosmetic and dermatological compositions in particular for the treatment of keratin containing substrates DR. STRAETMANS CHEMISCHE PRODUKTE GMBH (DE) 2011-11-15 US disclosed
EP-1257246-B2 PERSONAL CARE ARTICLES COMPRISING BATTING PROCTER & GAMBLE (US) 2009-12-09 EP disclosed
EP-2110121-A1 Cosmetic and dermatological compositions in particular for the treatment of keratin containing substrates Dr. Straetmans Chemische Produkte GmbH (DE) 2009-10-21 EP disclosed
US-20090257972-A1 COSMETIC AND DERMATOLOGICAL COMPOSITIONS IN PARTICULAR FOR THE TREATMENT OF KERATIN CONTAINING SUBSTRATES EVONIK OPERATIONS GMBH (DE) 2009-10-15 US disclosed
US-7115535-B1 Personal care articles comprising batting THE PROCTER & GAMBLE COMPANY (US) 2006-10-03 US disclosed
EP-1204360-B1 PERSONAL CARE ARTICLES PROCTER & GAMBLE (US) 2006-06-14 EP disclosed
EP-1257246-B1 PERSONAL CARE ARTICLES COMPRISING BATTING PROCTER & GAMBLE (US) 2006-03-08 EP disclosed
CN-1423549-A Personal care articles comprising hydrophilic conditioning agents with defined leach values PROCTER & GAMBLE (US) 2003-06-11 CN disclosed
CN-1377256-A Personal care articles PROCTER & GAMBLE (US) 2002-10-30 CN disclosed
US-6428799-B1 DRY, DISPOSABLE CLEANSER AND/OR CONDITIONER FOR SKIN AND HAIR; LOW DENSITY, NONSCOURING SYNTHETIC FIBER BATTING LAYER CONTAINING LATHERING SURFACTANT; NONIRRITATING THE PROCTER & GAMBLE COMPANY 2002-08-06 US disclosed
US-6322801-B1 Personal care articles THE PROCTER & GAMBLE COMPANY 2001-11-27 US disclosed
US-6267975-B1 DISPOSABLE, PERSONAL CARE ARTICLES USEFUL FOR CLEANSING AND/OR THERAPEUTICALLY TREATING SKIN, HAIR THE PROCTER & GAMBLE COMPANY 2001-07-31 US disclosed
US-6217889-B1 DISPOSABLE PRODUCT; CLEANING COMPOUNDS THE PROCTOR & GAMBLE COMPANY 2001-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090257972-A1 COSMETIC AND DERMATOLOGICAL COMPOSITIONS IN PARTICULAR FOR THE TREATMENT OF KERATIN CONTAINING SUBSTRATES KRT18, DPM1, TYR TSHR 3115/4885ZDHHC20 2134/4885ZDHHC2 2960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.