Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 2/20 | 0.86 |
| ▸ | NUDT1 | P36639 | 4/20 | 0.65 |
| ▸ | IKBKB | O14920 | 3/20 | 0.63 |
| ▸ | CHUK | O15111 | 3/20 | 0.63 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.55 |
| ▸ | CDK8 | P49336 | 2/20 | 0.55 |
| ▸ | CDK7 | P50613 | 2/20 | 0.55 |
| ▸ | CDK9 | P50750 | 2/20 | 0.55 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.55 |
| ▸ | PAK4 | O96013 | 2/20 | 0.55 |
| ▸ | CSF1R | P07333 | 2/20 | 0.55 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.55 |
| ▸ | FLT1 | P17948 | 2/20 | 0.55 |
| ▸ | KDR | P35968 | 2/20 | 0.55 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.55 |
| ▸ | CLK2 | P49760 | 2/20 | 0.55 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.55 |
| ▸ | PRKX | P51817 | 2/20 | 0.55 |
| ▸ | JAK3 | P52333 | 2/20 | 0.55 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10125558 | 0.92 | PRKCI (1.00) | PRKCINUDT1IKBKBCHUKAURKB | |
| SCHEMBL4762982 | 0.83 | PRKCI (0.60) | PRKCINUDT1AURKBCDK8CDK7 | |
| SCHEMBL857184 | 0.81 | PRKCI (0.78) | PRKCINUDT1IKBKBCHUKAURKB | |
| SCHEMBL4832761 | 0.80 | PRKCI (0.76) | PRKCINUDT1IKBKBCHUKAURKB | |
| SCHEMBL10125138 | 0.80 | IKBKB (0.84) | PRKCINUDT1IKBKBCHUKAURKB | |
| SCHEMBL19608468 | 0.80 | PRKCI (0.76) | PRKCINUDT1IKBKBCHUKAURKB | |
| SCHEMBL856859 | 0.80 | PRKCI (0.76) | PRKCINUDT1IKBKBCHUKAURKB | |
| SCHEMBL4772891 | 0.79 | NUDT1 (1.00) | PRKCINUDT1IKBKBCHUKAURKB | |
| SCHEMBL4791545 | 0.78 | PRKCI (0.72) | PRKCINUDT1IKBKBCHUKAURKB | |
| SCHEMBL4791550 | 0.78 | PRKCI (0.72) | PRKCINUDT1IKBKBCHUKAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934181-A2 | KINASE INHIBITORS | Devgen NV (BE) | 2008-06-25 | — | — | EP | claimed |
| WO-2007042321-A2 | KINASE INHIBITORS | DEVGEN N.V. (BE) | 2007-04-19 | — | — | WO | claimed |