Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.35 |
| ▸ | FAP | Q12884 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.35 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808993 | 0.94 | DPP4 (0.42) | DPP4LMNACYP2C19HSD17B10DPP8 | |
| SCHEMBL1592790 | 0.82 | LMNA (0.40) | DPP4GAAHPGDLMNACYP2C19 | |
| SCHEMBL9917272 | 0.82 | CHRM2 (0.42) | GAAHPGDLMNACHRM2CHRM4 | |
| SCHEMBL4796723 | 0.81 | KMT2A (0.33) | DPP4DPP8DPP9DPP7CA12 | |
| SCHEMBL16794429 | 0.81 | NAMPT (0.36) | DPP4GAAHPGDDPP8DPP9 | |
| SCHEMBL21340915 | 0.80 | DPP4 (0.42) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL23046549 | 0.79 | LMNA (0.41) | DPP4GAAHPGDLMNACYP2C19 | |
| SCHEMBL16253007 | 0.79 | GAA (0.48) | GAAHPGDLMNA | |
| SCHEMBL16253016 | 0.78 | ALDH1A1 (0.43) | HPGDCA2 | |
| SCHEMBL21340912 | 0.78 | DPP4 (0.36) | DPP4GAAHPGDDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931667-A1 | PYRIDO-PYRIDIMIDINE DERIVATIVES USEFUL AS ANTIINFLAMMATORY AGENTS | Ranbaxy Laboratories Limited (IN) | 2008-06-18 | — | — | EP | claimed |
| WO-2007036791-A1 | PYRIDO-PYRIDIMIDINE DERIVATIVES USEFUL AS ANTIINFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (US) | 2007-04-05 | — | — | WO | claimed |