Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | F2 | P00734 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.48 |
| ▸ | WNT3A | P56704 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9316435 | 0.88 | KDM4E (0.51) | NPC1RAB9AF2MEN1KMT2A | |
| SCHEMBL7190222 | 0.88 | HPGD (0.50) | NPC1RAB9AF2MEN1KMT2A | |
| SCHEMBL7190492 | 0.85 | HSD17B10 (0.59) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL6204029 | 0.84 | NPC1 (0.55) | NPC1RAB9AMEN1KMT2AHSD11B1 | |
| SCHEMBL7198317 | 0.84 | F2 (0.63) | NPC1RAB9AF2MEN1KMT2A | |
| SCHEMBL6202582 | 0.80 | ACHE (0.59) | NPC1RAB9AMEN1KMT2ACTNNB1 | |
| SCHEMBL30871956 | 0.80 | CYP3A4 (0.56) | MEN1KMT2APOLBNPSR1CYP3A4 | |
| SCHEMBL490437 | 0.80 | CYP3A4 (0.56) | MEN1KMT2APOLBNPSR1CYP3A4 | |
| SCHEMBL7190554 | 0.79 | NPC1 (0.51) | NPC1RAB9AF2MEN1KMT2A | |
| SCHEMBL7193965 | 0.79 | CYP3A4 (0.51) | NPC1RAB9AMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008208134-A | PROCESS FOR PREPARATION OF PHARMACOLOGICALLY ACTIVE alpha-ASARONE DERIVED FROM TOXIC beta-ASARONE-RICH CALAMUS OIL | COUNCIL SCIENT IND RES | 2008-09-11 | — | — | JP | disclosed |