Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8853339 | 0.90 | NPC1 (0.65) | NPC1RAB9AL3MBTL1HTTMTNR1A | |
| SCHEMBL17670831 | 0.88 | ALDH1A1 (0.51) | NPC1RAB9AL3MBTL1MTNR1AMTNR1B | |
| SCHEMBL29007489 | 0.86 | GAA (0.64) | NPC1RAB9AL3MBTL1HTTHSD11B1 | |
| SCHEMBL29007473 | 0.85 | CTNNB1 (0.64) | NPC1RAB9AHTTMTNR1AMTNR1B | |
| SCHEMBL7190492 | 0.84 | HSD17B10 (0.59) | NPC1RAB9AL3MBTL1MTNR1AMTNR1B | |
| SCHEMBL362209 | 0.84 | LMNA (0.59) | POLBNPSR1MTNR1AMTNR1BTAAR1 | |
| SCHEMBL29590071 | 0.84 | LMNA (0.59) | POLBNPSR1MTNR1AMTNR1BTAAR1 | |
| SCHEMBL4765104 | 0.84 | NPC1 (0.53) | NPC1RAB9AL3MBTL1POLBHTT | |
| SCHEMBL2336465 | 0.83 | NPC1 (0.59) | NPC1RAB9AL3MBTL1HTTMTNR1A | |
| SCHEMBL7198317 | 0.83 | F2 (0.63) | NPC1RAB9APOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116199597-A | Substituted phenyl diazonium salt and application thereof in catalytic preparation of 3-substituted indole compounds | 盐城利民农化有限公司 | 2023-06-02 | — | — | CN | claimed |
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |