Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.40 |
| ▸ | TUBB | P07437 | 2/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.40 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4772581 | 0.87 | HPGD (0.42) | MAOBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14145729 | 0.73 | HPGD (0.42) | MAOBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16517618 | 0.72 | HCAR3 (0.48) | HPGDCYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL4774522 | 0.71 | HPGD (0.43) | MAOBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16517241 | 0.71 | MAPT (0.44) | HPGDSMN1; SMN2NPC1CYP1A2CYP2D6 | |
| SCHEMBL2524672 | 0.71 | GAA (0.43) | MAOBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL15574129 | 0.70 | MMP2 (0.44) | ALOX15ALDH1A1KMT2AHTT | |
| SCHEMBL24679021 | 0.70 | EIF4A3 (0.37) | SMN1; SMN2MAPTALDH1A1KMT2A | |
| SCHEMBL75565 | 0.69 | KDM4E (0.51) | MAOBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16517756 | 0.69 | PTGER4 (0.50) | SMN1; SMN2NPC1RAB9AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732933-B1 | COMPOUNDS FOR TREATING DYSLIPIDEMIA | LILLY CO ELI (US) | 2008-07-23 | — | — | EP | disclosed |