Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.53 |
| ▸ | NPC1 | O15118 | 12/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.53 |
| ▸ | MEN1 | O00255 | 8/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4770904 | 0.94 | RAB9A (0.52) | RAB9ANPC1KMT2AMEN1GFER | |
| SCHEMBL4770201 | 0.84 | SMN1; SMN2 (0.50) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL4772409 | 0.83 | RAB9A (0.51) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL6299436 | 0.82 | RAB9A (0.57) | RAB9ANPC1KMT2AMEN1GFER | |
| SCHEMBL12748847 | 0.81 | RAB9A (0.46) | RAB9ANPC1KMT2AMEN1GFER | |
| SCHEMBL4775503 | 0.81 | MAPT (0.54) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL4768058 | 0.78 | NPC1 (0.69) | RAB9ANPC1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL4765225 | 0.78 | HRH3 (0.55) | RAB9ANPC1MAPTSMN1; SMN2TP53 | |
| SCHEMBL4768020 | 0.78 | SLC2A1 (0.53) | RAB9ANPC1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL4765905 | 0.78 | NPC1 (0.69) | RAB9ANPC1KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | claimed |