Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.51 |
| ▸ | NPC1 | O15118 | 11/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.48 |
| ▸ | RELA | Q04206 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4772603 | 0.94 | SLC2A1 (0.50) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL4770201 | 0.87 | SMN1; SMN2 (0.50) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL4775503 | 0.83 | MAPT (0.54) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL4765563 | 0.83 | RAB9A (0.53) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL4765111 | 0.81 | HRH3 (0.46) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL4768058 | 0.81 | NPC1 (0.69) | RAB9ANPC1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL4768020 | 0.81 | SLC2A1 (0.53) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL4765905 | 0.81 | NPC1 (0.69) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL4765225 | 0.81 | HRH3 (0.55) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL4774510 | 0.81 | RAB9A (0.57) | RAB9ANPC1MAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | claimed |