SCHEMBL4765634

SCHEMBL4765634

C=CCCCCOc1ccc(C(=O)OCCC(C)=C(F)F)cn1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LSS P48449 2/20 0.41
L3MBTL1 Q9Y468 4/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.35
LMNA P02545 2/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CHRNB2 P17787 1/20 0.32
CHRNA7 P36544 1/20 0.32
CHRNA4 P43681 1/20 0.32
PDE4B Q07343 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4771199 0.87 MAPT (0.42) L3MBTL1MAPTLMNACHRNB2CHRNA7
SCHEMBL4771394 0.86 LMNA (0.46) L3MBTL1ALDH1A1MAPTLMNAMEN1
SCHEMBL4770536 0.85 LMNA (0.48) L3MBTL1ALDH1A1MAPTLMNAMEN1
SCHEMBL4767243 0.85 LMNA (0.48) L3MBTL1ALDH1A1MAPTLMNAMEN1
SCHEMBL4763085 0.85 LMNA (0.48) L3MBTL1ALDH1A1MAPTLMNAMEN1
SCHEMBL4763551 0.85 L3MBTL1 (0.46) L3MBTL1ALDH1A1MAPTLMNAMEN1
SCHEMBL4767239 0.84 MAPT (0.43) L3MBTL1ALDH1A1MAPTLMNA
SCHEMBL4762510 0.83 MAPT (0.54) L3MBTL1ALDH1A1MAPTLMNAPDE4B
SCHEMBL4763360 0.81 L3MBTL1 (0.47) L3MBTL1ALDH1A1MAPTLMNAMEN1
SCHEMBL4763338 0.81 MAPT (0.45) L3MBTL1ALDH1A1MAPTLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1439169-B1 DIFLUOROALKENE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE SAME, AND INTERMEDIATE THEREFOR KUMIAI CHEMICAL INDUSTRY CO (JP) 2008-08-06 EP disclosed
US-7273878-B2 Difluoroalkene derivative, pest control agent containing the same, and intermediate therefor KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2007-09-25 US disclosed
US-20040248872-A1 Difluoroalkene derivative, pest control agent containing the same, and intermediate therefor IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 2004-12-09 US disclosed
EP-1439169-A1 DIFLUOROALKENE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE SAME, AND INTERMEDIATE THEREFOR KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2004-07-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040248872-A1 Difluoroalkene derivative, pest control agent containing the same, and intermediate therefor DDT, WEE1, NOTUM LSS 92/4885L3MBTL1 17/4885ALDH1A1 875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.