Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4763784 | 0.80 | KDM4E (0.61) | TP53SMN1; SMN2MAPTMAPK1HPGD | |
| SCHEMBL4770653 | 0.78 | HIF1A (0.41) | MAPK1HPGDHSD17B10TDP1 | |
| SCHEMBL1176572 | 0.76 | TP53 (0.67) | TP53SMN1; SMN2MAPTMAPK1POLB | |
| SCHEMBL4763863 | 0.75 | ALDH1A1 (0.54) | SMN1; SMN2MAPTHPGDNPC1RAB9A | |
| SCHEMBL4769039 | 0.73 | HDAC3 (0.47) | SMN1; SMN2MAPTKDM4ENPC1RAB9A | |
| SCHEMBL4767304 | 0.73 | NR4A2 (0.52) | MAPK1KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL4769492 | 0.72 | TSHR (0.41) | TP53MAPTMAPK1HSD17B10POLB | |
| SCHEMBL4764999 | 0.72 | HDAC3 (0.48) | SMN1; SMN2MAPTKDM4ENPC1RAB9A | |
| SCHEMBL4770615 | 0.72 | APP (0.55) | SMN1; SMN2HSD17B10KDM4ENPC1ALDH1A1 | |
| SCHEMBL19142574 | 0.71 | TP53 (0.61) | TP53SMN1; SMN2MAPTMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1439169-B1 | DIFLUOROALKENE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE SAME, AND INTERMEDIATE THEREFOR | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2008-08-06 | — | — | EP | disclosed |
| US-7273878-B2 | Difluoroalkene derivative, pest control agent containing the same, and intermediate therefor | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-09-25 | — | — | US | disclosed |
| US-20040248872-A1 | Difluoroalkene derivative, pest control agent containing the same, and intermediate therefor | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-12-09 | — | — | US | disclosed |
| EP-1439169-A1 | DIFLUOROALKENE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE SAME, AND INTERMEDIATE THEREFOR | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-07-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248872-A1 | Difluoroalkene derivative, pest control agent containing the same, and intermediate therefor | DDT, WEE1, NOTUM | TP53 1193/4885SMN1; SMN2 2115/4885MAPT 4388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.