Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | MGMT | P16455 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
| ▸ | PTAFR | P25105 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4775904 | 0.85 | CYP11B1 (0.39) | CYP11B1CYP11B2CYP19A1GRM2MGMT | |
| SCHEMBL4769070 | 0.80 | SMN1; SMN2 (0.39) | CYP11B1CYP11B2CYP19A1GRM2MGMT | |
| SCHEMBL4766386 | 0.77 | CYP11B1 (0.38) | CYP11B1CYP11B2CYP19A1GRM2MGMT | |
| SCHEMBL5340881 | 0.74 | MAPT (0.37) | CYP11B1CYP11B2CYP19A1GRM2MGMT | |
| SCHEMBL4793392 | 0.69 | CDK5 (0.41) | CYP11B1CYP11B2CYP19A1PTAFRPOLB | |
| SCHEMBL5339398 | 0.68 | ACP1 (0.39) | CYP11B1CYP11B2CYP19A1MGMTPTAFR | |
| SCHEMBL6696621 | 0.67 | ACHE (0.42) | — | |
| SCHEMBL4775908 | 0.65 | CYP11B1 (0.39) | CYP11B1CYP11B2CYP19A1GRM2MGMT | |
| SCHEMBL562914 | 0.64 | CDK5 (0.48) | POLBTDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL14524266 | 0.64 | TDP1 (0.64) | PTAFRTDP1L3MBTL1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513524-A4 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES CO (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1513524-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M Innovative Properties Company (US) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003103584-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-12-18 | — | — | WO | disclosed |