Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | PTAFR | P25105 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | BCL6 | P41182 | 1/20 | 0.38 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 3/20 | 0.37 |
| ▸ | GSK3B | P49841 | 3/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4769070 | 0.83 | SMN1; SMN2 (0.39) | CDK5CDK5R1PTAFRSMN1; SMN2MAPT | |
| SCHEMBL5340881 | 0.82 | MAPT (0.37) | CDK5CDK5R1PTAFRSMN1; SMN2MAPT | |
| SCHEMBL5339398 | 0.74 | ACP1 (0.39) | PTAFRSMN1; SMN2MAPTALDH1A1GSK3A | |
| SCHEMBL1052684 | 0.73 | GSK3A (0.48) | CDK5CDK5R1PTAFRSMN1; SMN2MAPT | |
| SCHEMBL6696621 | 0.72 | ACHE (0.42) | BCHEACHE | |
| SCHEMBL4775513 | 0.71 | LMNA (0.37) | PTAFRSMN1; SMN2MAPTALDH1A1TP53 | |
| SCHEMBL22456637 | 0.69 | KAT2B (0.54) | MAPTHTTPOLBALDH1A1HTR6 | |
| SCHEMBL4766384 | 0.69 | CYP11B1 (0.38) | PTAFRSMN1; SMN2POLBCYP19A1CYP11B1 | |
| SCHEMBL4936233 | 0.67 | MAPT (0.56) | CDK5CDK5R1SMN1; SMN2MAPTHTT | |
| SCHEMBL4773222 | 0.67 | CHRNA7 (0.56) | PTAFRSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513524-A4 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES CO (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1513524-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M Innovative Properties Company (US) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003103584-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-12-18 | — | — | WO | disclosed |