Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4506656 | 0.94 | ALDH1A1 (0.38) | ALDH1A1HPGDTSHRSMN1; SMN2LMNA | |
| SCHEMBL10525669 | 0.84 | BRD4 (0.39) | ALDH1A1TSHRLMNABRD4BRD2 | |
| SCHEMBL1440029 | 0.82 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2LMNAPOLBBRD4 | |
| SCHEMBL442676 | 0.80 | BRD4 (0.44) | ALDH1A1HPGDTSHRLMNABRD4 | |
| SCHEMBL2997559 | 0.78 | BRD4 (0.42) | ALDH1A1HPGDTSHRLMNAPOLB | |
| SCHEMBL1440028 | 0.77 | BRD4 (0.43) | ALDH1A1TSHRLMNABRD4BRD2 | |
| SCHEMBL1974003 | 0.75 | KDM4E (0.33) | ALDH1A1SMN1; SMN2POLBBRD4BRD2 | |
| SCHEMBL2927812 | 0.75 | CHRM2 (0.33) | BRD4BRD2 | |
| SCHEMBL2363506 | 0.74 | BRD4 (0.48) | ALDH1A1TSHRLMNABRD4BRD2 | |
| SCHEMBL11382367 | 0.74 | BRD4 (0.42) | ALDH1A1SMN1; SMN2LMNAPOLBBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896471-A1 | IMIDAZOPYRIDINE DERIVATIVES AS ACID PUMP ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-03-12 | — | — | EP | claimed |
| WO-2007003386-A1 | IMIDAZOPYRIDINE DERIVATIVES AS ACID PUMP ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2007-01-11 | — | — | WO | claimed |