Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 4/20 | 0.46 |
| ▸ | CALML3 | P27482 | 3/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | PTH1R | Q03431 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4724953 | 0.86 | GRM2 (0.44) | GRM2CALML3S1PR5 | |
| SCHEMBL4766697 | 0.83 | GRM2 (0.45) | GRM2CALML3S1PR5 | |
| SCHEMBL17769259 | 0.83 | GRM2 (0.47) | GRM2CALML3S1PR5 | |
| SCHEMBL541807 | 0.83 | CALML3 (0.59) | GRM2CALML3S1PR5 | |
| SCHEMBL541806 | 0.83 | CALML3 (0.59) | GRM2CALML3S1PR5 | |
| SCHEMBL2837784 | 0.83 | GRM2 (0.47) | GRM2CALML3S1PR5 | |
| SCHEMBL9611100 | 0.83 | GRM2 (0.49) | GRM2CALML3S1PR5 | |
| SCHEMBL17769261 | 0.83 | GRM2 (0.47) | GRM2CALML3S1PR5 | |
| SCHEMBL4766969 | 0.81 | CALML3 (0.50) | CALML3 | |
| SCHEMBL2845028 | 0.80 | CYP3A4 (0.47) | CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931684-A2 | OXAZOLIDINONE-QUINOLONE HYBRIDS AS ANTIBACTERIAL COMPOUNDS | Actelion Pharmaceuticals Ltd. (CH) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007017828-A2 | OXAZOLIDINONE-QUINOLONE HYBRIDS AS ANTIBACTERIAL COMPOUNDS | ACTELION PHARMACEUTICALS LTD (CH) | 2007-02-15 | — | — | WO | disclosed |