SCHEMBL4767155

SCHEMBL4767155

OCCCCC1COCCO1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.42
CHRM4 P08173 1/20 0.42
CHRM5 P08912 1/20 0.42
CHRM3 P20309 1/20 0.42
ALDH1A1 P00352 2/20 0.41
THRB P10828 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
EPHX1 P07099 1/20 0.36
GPR84 Q9NQS5 1/20 0.31
PRKD3 O94806 1/20 0.30
PRKCG P05129 1/20 0.30
PRKCB P05771 1/20 0.30
PRKCA P17252 1/20 0.30
PRKCH P24723 1/20 0.30
PRKCI P41743 1/20 0.30
PRKCE Q02156 1/20 0.30
PRKCQ Q04759 1/20 0.30
PRKCZ Q05513 1/20 0.30
PRKCD Q05655 1/20 0.30
PRKD1 Q15139 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4773015 1.00 CHRM2 (0.42) CHRM2CHRM4CHRM5CHRM3ALDH1A1
SCHEMBL8928379 0.98 ALDH1A1 (0.43) CHRM2CHRM4CHRM5CHRM3ALDH1A1
Methyl Alcohol SCHEMBL28701156 0.96 CHRM2 (0.44) CHRM2CHRM4CHRM5CHRM3ALDH1A1
SCHEMBL4667952 0.94 CHRM2 (0.44) CHRM2CHRM4CHRM5CHRM3ALDH1A1
Oxirane SCHEMBL9245218 0.87 ALDH1A1 (0.52) ALDH1A1THRBSMN1; SMN2EPHX1PRKD3
SCHEMBL26986006 0.85
SCHEMBL928477 0.85
SCHEMBL8079198 0.83 CHRM2 (0.45) CHRM2CHRM4CHRM5CHRM3ALDH1A1
SCHEMBL8071010 0.83 CHRM2 (0.45) CHRM2CHRM4CHRM5CHRM3ALDH1A1
Water SCHEMBL5064656 0.83 CHRM2 (0.45) CHRM2CHRM4CHRM5CHRM3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115308171-A Preparation method and application of fluorescence/electrochemistry bimodal nanosensor based on covalent organic framework 江苏大学 2022-11-08 CN claimed
CN-115165992-A Construction and application of AuNPs @ COFs-MWCNTs composite material modified electrode 河北科技大学 2022-10-11 CN claimed
CN-118895271-A Functionalized nucleic acid probe, electrochemical biosensor, preparation method and application 河北科技大学 2024-11-05 CN disclosed
CN-218766625-U Fluorescence/electrochemistry bimodal microfluidic detection device 江苏大学 2023-03-28 CN disclosed
CN-115308171-A Preparation method and application of fluorescence/electrochemistry bimodal nanosensor based on covalent organic framework 江苏大学 2022-11-08 CN disclosed
CN-114047341-B Biological probe and biological immunosensor for detecting bungarus venosus and method for detecting bungarus venosus based on proportional signal 云南大学 2022-10-18 CN disclosed
CN-115165992-A Construction and application of AuNPs @ COFs-MWCNTs composite material modified electrode 河北科技大学 2022-10-11 CN disclosed
CN-114047341-A Biological probe and biological immunosensor for detecting bungarus venosus and method for detecting bungarus venosus based on proportional signal 云南大学 2022-02-15 CN disclosed
EP-2751094-B1 NOVEL CRYSTAL FORM GLAXO GROUP LTD (GB) 2018-06-20 EP disclosed
US-9694004-B2 Crystal form GLAXO GROUP LIMITED (GB) 2017-07-04 US disclosed
US-20160367544-A1 Novel Crystal Form GLAXO GROUP LIMITED (GB) 2016-12-22 US disclosed
EP-2764866-A1 Inhibitors of nedd8-activating enzyme IP Gesellschaft für Management mbH (DE) 2014-08-13 EP disclosed
EP-2751094-A1 NOVEL CRYSTAL FORM Glaxo Group Limited (GB) 2014-07-09 EP disclosed
WO-2013030374-A1 NOVEL CRYSTAL FORM GLAXO GROUP LIMITED (GB) 2013-03-07 WO disclosed
CN-101709313-B Method for catalytic synthesizing beta-nitroalcohol compounds by using lipase in organic phase ZHEJIANG UNIVERSITY (CN) 2011-12-07 CN disclosed
CN-101899052-A B-crystal form solid matter of bergenin and preparation method and application thereof INST MATERIA MEDICA CAMS 2010-12-01 CN disclosed
CN-101709313-A Method for catalytic synthesizing beta-nitroalcohol compounds by using lipase in organic phase UNIV ZHEJIANG 2010-05-19 CN disclosed
EP-1942892-A1 SOLID DISPERSIONS OF OPIOID ANTAGONISTS Adolor Corporation (US) 2008-07-16 EP disclosed
WO-2007044713-A1 SOLID DISPERSIONS OF OPIOID ANTAGONISTS ADOLOR CORPORATION (US) 2007-04-19 WO disclosed
US-5037748-A From phthalic acid or salt using a microorganism, acidification, solvent extraction JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-08-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160367544-A1 Novel Crystal Form DDX21, NOLC1, GYS2 CHRM2 3759/4885CHRM4 3518/4885CHRM5 3368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.