Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | MDH2 | P40926 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | MATK | P42679 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL476838 | 1.00 | HPGD (0.45) | HPGDALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL8802912 | 0.86 | HPGD (0.54) | HPGDALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL9666677 | 0.84 | HPGD (0.54) | HPGDALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL29728320 | 0.79 | HPGD (0.52) | HPGDALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL10530599 | 0.79 | PIM3 (0.51) | HPGDALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL10529452 | 0.79 | HPGD (0.47) | HPGDALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL15557018 | 0.78 | HPGD (0.46) | HPGDALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL9443458 | 0.77 | HPGD (0.52) | HPGDALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL9051473 | 0.77 | HPGD (0.52) | HPGDALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL9596257 | 0.77 | HSD17B10 (0.59) | HPGDALDH1A1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8604020-B2 | Fluoroquinolone carboxylic acid molecular crystals | BAUSCH & LOMB INCORPORATED (US) | 2013-12-10 | — | — | US | claimed |
| US-20130252946-A1 | Fluoroquinolone Carboxylic Acid Molecular Crystals | BAUSCH & LOMB INCORPORATED (US) | 2013-09-26 | — | — | US | claimed |
| EP-2411369-A1 | FLUOROQUINOLONE CARBOXYLIC ACID MOLECULAR CRYSTALS | Bausch & Lomb Incorporated (US) | 2012-02-01 | — | — | EP | claimed |
| US-20110144329-A1 | Amorphous Besifloxacin Solid | ORAPHARMA, INC. | 2011-06-16 | — | — | US | claimed |
| US-20100311731-A1 | Fluoroquinolone Carboxylic Acid Molecular Crystals | SALIX PHARMACEUTICALS, INC. | 2010-12-09 | — | — | US | claimed |
| WO-2010111116-A1 | FLUOROQUINOLONE CARBOXYLIC ACID MOLECULAR CRYSTALS | BAUSCH & LOMB INCORPORATED (US) | 2010-09-30 | — | — | WO | claimed |
| US-8518935-B2 | Amorphous besifloxacin solid | BAUSCH & LOMB INCORPORATED (US) | 2013-08-27 | — | — | US | disclosed |
| CN-102369189-A | Fluoroquinolone carboxylic acid molecular crystals | BAUSCH & LOMB | 2012-03-07 | — | — | CN | disclosed |
| EP-2411369-A1 | FLUOROQUINOLONE CARBOXYLIC ACID MOLECULAR CRYSTALS | Bausch & Lomb Incorporated (US) | 2012-02-01 | — | — | EP | disclosed |
| EP-2411369-A1 | FLUOROQUINOLONE CARBOXYLIC ACID MOLECULAR CRYSTALS | Bausch & Lomb Incorporated (US) | 2012-02-01 | — | — | EP | disclosed |
| US-20110144329-A1 | Amorphous Besifloxacin Solid | ORAPHARMA, INC. | 2011-06-16 | — | — | US | disclosed |
| US-20110144329-A1 | Amorphous Besifloxacin Solid | ORAPHARMA, INC. | 2011-06-16 | — | — | US | disclosed |
| US-20100311731-A1 | Fluoroquinolone Carboxylic Acid Molecular Crystals | SALIX PHARMACEUTICALS, INC. | 2010-12-09 | — | — | US | disclosed |
| US-20100311731-A1 | Fluoroquinolone Carboxylic Acid Molecular Crystals | SALIX PHARMACEUTICALS, INC. | 2010-12-09 | — | — | US | disclosed |
| WO-2010111116-A1 | FLUOROQUINOLONE CARBOXYLIC ACID MOLECULAR CRYSTALS | BAUSCH & LOMB INCORPORATED (US) | 2010-09-30 | — | — | WO | disclosed |
| WO-2010111116-A1 | FLUOROQUINOLONE CARBOXYLIC ACID MOLECULAR CRYSTALS | BAUSCH & LOMB INCORPORATED (US) | 2010-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144329-A1 | Amorphous Besifloxacin Solid | SP1, ABCG2, YBX1 | HPGD 2867/4885ALDH1A1 2593/4885MEN1 4248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.