Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.52 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.51 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.48 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.48 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.48 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.48 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.48 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9666677 | 0.90 | HPGD (0.54) | HPGDMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL8802912 | 0.90 | HPGD (0.54) | HPGDMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL9443458 | 0.87 | HPGD (0.52) | HPGDMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL9288586 | 0.86 | HPGD (0.57) | HPGDMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL29728320 | 0.82 | HPGD (0.52) | HPGDMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL27541984 | 0.81 | HPGD (0.47) | HPGDMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL7740284 | 0.80 | JAK2 (0.49) | HPGDMEN1KMT2AALDH1A1GAA | |
| SCHEMBL5307312 | 0.79 | KDM4E (0.49) | HPGDMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL9596257 | 0.79 | HSD17B10 (0.59) | HPGDMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL15557018 | 0.79 | HPGD (0.46) | HPGDMEN1KMT2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287951-B1 | 7-Piperazinyl- or 7-Morpholino-4-oxo-quinoline-3-carboxylic acid derivatives, their preparation and their use as antimicrobial agents | OTSUKA PHARMA CO LTD (JP) | 1996-07-03 | — | — | EP | disclosed |
| EP-0287951-A2 | 7-Piperazinyl- or 7-Morpholino-4-oxo-quinoline-3-carboxylic acid derivatives, their preparation and their use as antimicrobial agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-10-26 | — | — | EP | disclosed |