Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.51 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.50 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.49 |
| ▸ | DNASE1 | P24855 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.49 |
| ▸ | MDH2 | P40926 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9666677 | 0.97 | HPGD (0.54) | HPGDMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL9443458 | 0.90 | HPGD (0.52) | HPGDMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL9051473 | 0.90 | HPGD (0.52) | HPGDMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL9596257 | 0.89 | HSD17B10 (0.59) | HPGDMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL9288586 | 0.88 | HPGD (0.57) | HPGDMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL476730 | 0.86 | HPGD (0.45) | HPGDMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL476838 | 0.86 | HPGD (0.45) | HPGDMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL29728320 | 0.84 | HPGD (0.52) | HPGDMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL27541984 | 0.83 | HPGD (0.47) | HPGDMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL15557018 | 0.81 | HPGD (0.46) | HPGDMEN1KMT2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757990-A1 | 7-(1-Pyrrolidoinyl)-3-quinolone and naphthyridone carboxylic acid derivatives, method for their preparation and for substituted mono- and bicyclic pyrrolidine intermediates, and their antibacterial and feed additive compositions | BAYER AG (DE) | 1997-02-12 | — | — | EP | disclosed |