Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | LITAF | Q99732 | 1/20 | 0.34 |
| ▸ | PARG | Q86W56 | 2/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4766095 | 0.89 | MAPT (0.39) | MITFMAPTSMN1; SMN2POLBADORA2A | |
| SCHEMBL4766101 | 0.89 | MAPT (0.39) | MITFMAPTSMN1; SMN2POLBADORA2A | |
| SCHEMBL4793250 | 0.88 | NPC1 (0.37) | MITFMAPTSMN1; SMN2POLBADORA3 | |
| SCHEMBL4762306 | 0.85 | MAPT (0.42) | MITFMAPTSMN1; SMN2POLBMEN1 | |
| SCHEMBL4762304 | 0.85 | MAPT (0.42) | MITFMAPTSMN1; SMN2POLBMEN1 | |
| SCHEMBL4771540 | 0.84 | ADORA2B (0.40) | MITFMAPTADORA3ADORA2AADORA2B | |
| SCHEMBL4765619 | 0.83 | NCOA1 (0.41) | MITFMAPTSMN1; SMN2POLBMEN1 | |
| SCHEMBL4765603 | 0.83 | NCOA1 (0.41) | MITFMAPTSMN1; SMN2POLBMEN1 | |
| SCHEMBL4768028 | 0.83 | MAPK1 (0.39) | MITFMAPTSMN1; SMN2POLBADORA3 | |
| SCHEMBL4768016 | 0.83 | MAPK1 (0.39) | MITFMAPTSMN1; SMN2POLBADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678181-B1 | A2B ADENOSINE RECEPTOR ANTAGONISTS | CV THERAPEUTICS INC (US) | 2008-12-31 | — | — | EP | disclosed |