Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | IAPP | P10997 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28332846 | 0.89 | FOLH1 (0.58) | ALDH1A1LMNAFOLH1HTTSMN1; SMN2 | |
| SCHEMBL11858586 | 0.85 | FOLH1 (0.58) | ALDH1A1LMNAFOLH1HTTSMN1; SMN2 | |
| SCHEMBL29062 | 0.84 | FOLH1 (0.66) | ALDH1A1LMNAFOLH1HTTSMN1; SMN2 | |
| SCHEMBL70392 | 0.83 | FOLH1 (0.76) | ALDH1A1FOLH1HTTSMN1; SMN2ALOX15 | |
| SCHEMBL30365583 | 0.83 | FOLH1 (0.76) | ALDH1A1FOLH1HTTSMN1; SMN2ALOX15 | |
| SCHEMBL6365140 | 0.83 | ALDH1A1 (0.65) | ALDH1A1LMNAFOLH1HTTSMN1; SMN2 | |
| SCHEMBL27568253 | 0.82 | FOLH1 (0.63) | ALDH1A1LMNAFOLH1HTTSMN1; SMN2 | |
| SCHEMBL8878978 | 0.81 | ALDH1A1 (0.63) | ALDH1A1LMNAFOLH1HTTSMN1; SMN2 | |
| SCHEMBL28276976 | 0.81 | FOLH1 (0.58) | ALDH1A1LMNAFOLH1HTTIAPP | |
| SCHEMBL6800544 | 0.81 | FOLH1 (0.61) | ALDH1A1LMNAFOLH1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109369597-B | Synthetic method of isocoumarin compound | 陕西师范大学 | 2022-11-29 | — | — | CN | claimed |
| CN-109438408-A | A kind of synthetic method of Dihydroiso-coumarin class compound | 陕西师范大学 | 2019-03-08 | — | — | CN | claimed |
| CN-109369597-A | A kind of synthetic method of isocoumarin class compound | 陕西师范大学 | 2019-02-22 | — | — | CN | claimed |
| US-20240066136-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI), INC. (CN) | 2024-02-29 | — | — | US | disclosed |
| CN-109369597-B | Synthetic method of isocoumarin compound | 陕西师范大学 | 2022-11-29 | — | — | CN | disclosed |
| CN-109369597-B | Synthetic method of isocoumarin compound | 陕西师范大学 | 2022-11-29 | — | — | CN | disclosed |
| CN-109438408-A | A kind of synthetic method of Dihydroiso-coumarin class compound | 陕西师范大学 | 2019-03-08 | — | — | CN | disclosed |
| CN-109438408-A | A kind of synthetic method of Dihydroiso-coumarin class compound | 陕西师范大学 | 2019-03-08 | — | — | CN | disclosed |
| CN-109369597-A | A kind of synthetic method of isocoumarin class compound | 陕西师范大学 | 2019-02-22 | — | — | CN | disclosed |
| CN-109369597-A | A kind of synthetic method of isocoumarin class compound | 陕西师范大学 | 2019-02-22 | — | — | CN | disclosed |
| EP-1439169-B1 | DIFLUOROALKENE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE SAME, AND INTERMEDIATE THEREFOR | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2008-08-06 | — | — | EP | disclosed |
| US-7273878-B2 | Difluoroalkene derivative, pest control agent containing the same, and intermediate therefor | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-09-25 | — | — | US | disclosed |
| US-20040248872-A1 | Difluoroalkene derivative, pest control agent containing the same, and intermediate therefor | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-12-09 | — | — | US | disclosed |
| EP-1439169-A1 | DIFLUOROALKENE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE SAME, AND INTERMEDIATE THEREFOR | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-07-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240066136-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | DDB1, DCLRE1A, MDM2 | ALDH1A1 1427/4885LMNA 711/4885FOLH1 2138/4885 |
| US-20040248872-A1 | Difluoroalkene derivative, pest control agent containing the same, and intermediate therefor | DDT, WEE1, NOTUM | ALDH1A1 875/4885LMNA 4259/4885FOLH1 2427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.