Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SLC16A3 | O15427 | 4/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29062 | 0.86 | FOLH1 (0.66) | FOLH1ALDH1A1ALOX15TSHRLMNA | |
| SCHEMBL30365583 | 0.85 | FOLH1 (0.76) | FOLH1ALDH1A1ALOX15TSHRSLC16A3 | |
| SCHEMBL70392 | 0.85 | FOLH1 (0.76) | FOLH1ALDH1A1ALOX15TSHRSLC16A3 | |
| SCHEMBL11443185 | 0.83 | FOLH1 (0.57) | FOLH1ALDH1A1ALOX15TSHRHMGB1 | |
| SCHEMBL5157746 | 0.82 | ALDH1A1 (0.45) | FOLH1ALDH1A1TSHRLMNAKDM4E | |
| SCHEMBL4768892 | 0.82 | ALDH1A1 (0.67) | FOLH1ALDH1A1ALOX15TSHRLMNA | |
| SCHEMBL6800544 | 0.82 | FOLH1 (0.61) | FOLH1ALDH1A1ALOX15TSHRLMNA | |
| SCHEMBL31474045 | 0.81 | FOLH1 (0.70) | FOLH1ALDH1A1ALOX15TSHRSLC16A3 | |
| Ethylene SCHEMBL18893737 | 0.81 | FOLH1 (0.70) | FOLH1ALDH1A1ALOX15TSHRSLC16A3 | |
| SCHEMBL729909 | 0.81 | FOLH1 (0.70) | FOLH1ALDH1A1ALOX15TSHRSLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1398247-A | Colchicol derivatives as vascular damaging agents | ANGIOGENE PHARM LTD (GB) | 2003-02-19 | — | — | CN | disclosed |