⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28841410 | 1.00 | — | — | |
| Isobutyramide SCHEMBL18836923 | 0.77 | — | — | |
| Isobutyramide SCHEMBL11109750 | 0.75 | LMNA (0.46) | — | |
| Isobutyramide SCHEMBL3323 | 0.75 | — | — | |
| SCHEMBL1289823 | 0.74 | — | — | |
| SCHEMBL1289850 | 0.74 | — | — | |
| SCHEMBL7128203 | 0.74 | TDP1 (0.32) | — | |
| Isobutyramide SCHEMBL2402176 | 0.72 | — | — | |
| SCHEMBL10815842 | 0.72 | — | — | |
| SCHEMBL95564 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 714 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114727983-A | Xanthine CB1 inhibitors | 金翅雀生物公司 | 2022-07-08 | — | — | CN | claimed |
| WO-2021062089-A1 | XANTHINE CB1 INHIBITORS | GOLDFINCH BIO, INC. (US) | 2021-04-01 | — | — | WO | claimed |
| CN-107400193-A | A kind of application of new DOPO types compound in EP | 武汉工程大学 | 2017-11-28 | — | — | CN | claimed |
| CN-104447450-B | Cysteine amide-type pleuromutilin derivative and preparation method and medical usage | 南通大学 | 2016-09-28 | — | — | CN | claimed |
| CN-104961666-A | 2-mercaptoacetamide pleuromutilin derivatives, and preparation method and medical application thereof | UNIV NANTONG | 2015-10-07 | — | — | CN | claimed |
| CN-104447450-A | Cysteine amide type pleuromutilin derivative as well as preparation method and medical application thereof | UNIV NANTONG | 2015-03-25 | — | — | CN | claimed |
| EP-1133976-B1 | Hair dye composition | KAO CORP (JP) | 2007-02-28 | — | — | EP | claimed |
| US-20060089355-A1 | Methods of treating alzheimer's disease using aromatically substituted w-amino-alkanoic acid amides and alkanoic acid diamides | ELAN PHARMACEUTICALS, INC. | 2006-04-27 | — | — | US | claimed |
| WO-2003103652-A1 | METHODS OF TREATING ALZHEIMER’S DISEASE USING AROMATICALLY SUBSTITUTED ω-AMINO-ALKANOIC ACID AMIDES AND ALKANOIC ACID DIAMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | claimed |
| EP-1330443-A1 | SUBSTITUTED PHENYLURACILS | Bayer CropScience AG (DE) | 2003-07-30 | — | — | EP | claimed |
| US-4665073-A | HISTAMINE H2-ANTAGONISTS | ICI AMERICAS INC. (GB) | 1987-05-12 | — | — | US | claimed |
| EP-0060094-B1 | GUANIDINE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-01-22 | — | — | EP | claimed |
| EP-0150099-A1 | Guanidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-07-31 | — | — | EP | claimed |
| US-4496564-A | HISTAMINE H-2 ANTIGONISTS | ICI AMERICAS INC. (US) | 1985-01-29 | — | — | US | claimed |
| EP-0050072-B1 | CYCLOPROPYL METHYL PIPERAZINES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THERAPEUTICS | INNOTHERA (FR) | 1984-12-27 | — | — | EP | claimed |
| US-4447441-A | ANTIHISTAMINE, ANTIULCER AND ANTISECRETORY AGENT | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-05-08 | — | — | US | claimed |
| EP-0060094-A2 | Guanidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-15 | — | — | EP | claimed |
| EP-0060093-A2 | Amide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-15 | — | — | EP | claimed |
| US-4113717-A | Quaternized azo dyestuffs | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-09-12 | — | — | US | claimed |
| US-4014920-A | N-cinnamylcarbamic acid esters | CIBA-GEIGY CORPORATION (US) | 1977-03-29 | — | — | US | claimed |