Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Isobutyramide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isobutyramide SCHEMBL28256794 | 1.00 | LMNA (0.43) | — | |
| Isobutyramide SCHEMBL7090821 | 1.00 | — | — | |
| Isobutyramide SCHEMBL68431 | 1.00 | — | — | |
| Isobutyramide SCHEMBL27318890 | 0.96 | — | — | |
| Isobutyramide SCHEMBL27782244 | 0.96 | — | — | |
| Isobutyramide SCHEMBL27733619 | 0.96 | — | — | |
| Isobutyramide SCHEMBL2829019 | 0.96 | — | — | |
| Isobutyramide SCHEMBL11109750 | 0.96 | LMNA (0.46) | — | |
| Isobutyramide SCHEMBL3323 | 0.96 | — | — | |
| Isobutyramide SCHEMBL5830040 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 358 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166140-B | CDK8/19 inhibitors | 拜奥卡德联合股份公司 | 2024-06-14 | — | — | CN | claimed |
| CN-117924718-B | Modified sodium carboxymethyl cellulose and preparation method thereof | 恒达亲水胶体泰州有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-117187137-B | Screening and preparation method for sewage treatment microbial inoculum | 南通苏润环保科技有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-115677925-B | Constant-rheological stabilizer, drilling fluid and preparation method thereof | 中国石油天然气集团有限公司 | 2024-04-30 | — | — | CN | claimed |
| CN-117924718-A | Modified sodium carboxymethyl cellulose and preparation method thereof | 恒达亲水胶体泰州有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-117899934-A | Chlorine-containing mildew amine organic porous polymer catalyst and synthetic method and application thereof | 上海理工大学 | 2024-04-19 | — | — | CN | claimed |
| CN-116554396-B | Polyacrylonitrile nanosphere modified polyacrylamide-acrylic acid gel electrolyte, preparation method and application thereof | 中国海洋大学 | 2024-04-19 | — | — | CN | claimed |
| CN-117903534-A | Synthesis method of double-tracing polystyrene nano-spheres | 四川农业大学 | 2024-04-19 | — | — | CN | claimed |
| CN-117362518-A | Ultra-deep water gas hydrate kinetic inhibitor and preparation method and application thereof | 中海油海南能源有限公司 | 2024-01-09 | — | — | CN | claimed |
| CN-117219442-A | Conductive polypyrrole nano microsphere and conductive hydrogel electrode material thereof | 南京林业大学 | 2023-12-12 | — | — | CN | claimed |
| CN-105859679-A | Compound and polymer prepared by using same | 财团法人工业技术研究院 | 2016-08-17 | — | — | CN | claimed |
| CN-105297538-A | High molecular reinforcing agent for paper, as well as preparation method and application of reinforcing agent | UNIV JIANGNAN | 2016-02-03 | — | — | CN | claimed |
| CN-105294931-A | High molecular coagulant, as well as preparation method and application thereof | UNIV JIANGNAN | 2016-02-03 | — | — | CN | claimed |
| CN-104327219-A | Aqueous emulsion for basic binder of adhesive for hard-bonding materials and preparation method thereof | WUHAN JIEFENG JOINT ADHESIVE TECHNOLOGY CO LTD | 2015-02-04 | — | — | CN | claimed |
| CN-104178064-A | Composite pure waterborne hard-to-be-adhered material adhesive for packaging paper commodities and preparation method thereof | WUHAN JIEFENG JOINT ADHESIVE TECHNOLOGY CO LTD | 2014-12-03 | — | — | CN | claimed |
| CN-102269702-A | Detection kit for determining small berry ORAC (oxygen radical absorbance capacity) and detection method thereof | — | 2011-12-07 | — | — | CN | claimed |
| CN-101300708-B | Improved membrane-electrode assemblies and long-life fuel cells | BASF FUEL CELL GMBH | 2010-12-29 | — | — | CN | claimed |
| US-7754077-B1 | Dialysis membrane for separation on microchips | SANDIA CORPORATION (US) | 2010-07-13 | — | — | US | claimed |
| CN-101405304-A | Method for producing polymers in aqueous solvents | BASF SE (DE) | 2009-04-08 | — | — | CN | claimed |
| CN-101300708-A | Improved membrane-electrode assemblies and long-life fuel cells | BASF FUEL CELL GMBH (DE) | 2008-11-05 | — | — | CN | claimed |