Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 12/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | CKS1B | P61024 | 1/20 | 0.48 |
| ▸ | SKP1 | P63208 | 1/20 | 0.48 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4793955 | 0.87 | BDKRB1 (0.49) | CHRM4CHRM2 | |
| SCHEMBL5843717 | 0.86 | CHRM4 (0.61) | CHRM4CHRM2 | |
| SCHEMBL4703208 | 0.81 | CHRM4 (0.56) | CHRM4CHRM2BCHECKS1BSKP1 | |
| SCHEMBL3209065 | 0.77 | ME3 (0.63) | — | |
| SCHEMBL5383679 | 0.75 | MEN1 (0.54) | — | |
| SCHEMBL29432057 | 0.74 | CHRM4 (1.00) | CHRM4CHRM2 | |
| SCHEMBL4304769 | 0.74 | CHRM4 (0.51) | CHRM4CHRM2 | |
| SCHEMBL345540 | 0.74 | CHRM4 (0.51) | CHRM4CHRM2 | |
| SCHEMBL4718806 | 0.74 | BDKRB1 (0.52) | CHRM4CHRM2 | |
| SCHEMBL4071616 | 0.74 | ADRA1D (0.51) | CHRM4CHRM2CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572678-A4 | SUBSTITUTED N-PHENYL SULFONAMIDE BRADYKININ ANTAGONISTS | ELAN PHARM INC (US) | 2008-05-07 | — | — | EP | disclosed |
| EP-1572678-A2 | SUBSTITUTED N-PHENYL SULFONAMIDE BRADYKININ ANTAGONISTS | Elan Pharmaceuticals, Inc. (US) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004056319-A2 | SUBSTITUTED N-PHENYL SULFONAMIDE BRADYKININ ANTAGONISTS | ELAN PHARMACEUTICALS INC. (US) | 2004-07-08 | — | — | WO | disclosed |