SCHEMBL4770093

SCHEMBL4770093

[SiH3]OC(C1CCCCC1)C1CCCCC1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
HSD17B10 Q99714 1/20 0.38
EPHX1 P07099 2/20 0.36
SHBG P04278 1/20 0.36
TP53 P04637 1/20 0.33
KDM4E B2RXH2 1/20 0.32
GMNN O75496 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6057182 0.97 ALDH1A1 (0.33) ALDH1A1HSD17B10EPHX1SHBG
SCHEMBL28651064 0.76 SHBG (0.33) SHBG
SCHEMBL11055346 0.75 EPHX1 (0.39) ALDH1A1HSD17B10EPHX1SHBGTP53
SCHEMBL1404457 0.74 SHBG (0.40) ALDH1A1HSD17B10EPHX1SHBGTP53
SCHEMBL8955060 0.72 ALDH1A1 (0.36) ALDH1A1HSD17B10EPHX1SHBG
SCHEMBL8955943 0.72 ALDH1A1 (0.36) ALDH1A1HSD17B10EPHX1SHBG
SCHEMBL8955257 0.72 ALDH1A1 (0.36) ALDH1A1HSD17B10EPHX1SHBG
SCHEMBL28651062 0.71 EPHX1 (0.33) EPHX1SHBGTP53KDM4EGMNN
SCHEMBL25082862 0.71 IDO1 (0.43) EPHX1SHBGTP53KDM4EGMNN
SCHEMBL15619308 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109641482-B Preparation of cis-1, 4-polydienes having multiple silane functional groups prepared by in situ hydrosilylation of polymer glues 株式会社普利司通 2021-11-05 CN disclosed
EP-1832351-B1 Low dielectric materials and methods for making same AIR PROD & CHEM (US) 2008-11-12 EP disclosed
EP-1837086-A2 Low dielectric materials and methods for making same Air Products and Chemicals, Inc. (US) 2007-09-26 EP disclosed
EP-1832351-A2 Low dielectric materials and methods for making same Air Products and Chemicals, Inc. (US) 2007-09-12 EP disclosed
EP-1159315-B1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEM CO (US) 2006-09-06 EP disclosed
US-20050260420-A1 Low dielectric materials and methods for making same VERSUM MATERIALS US, LLC 2005-11-24 US disclosed
EP-1192196-B1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEM CO (US) 2005-07-13 EP disclosed
EP-1183284-B1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEM CO (US) 2005-04-27 EP disclosed
EP-1464410-A1 Low dielectric materials and methods for making same AIR PRODUCTS AND CHEMICALS, INC. (US) 2004-10-06 EP disclosed
US-6696380-B2 Procatalysts, catalyst systems, and use in olefin polymerization WESTLAKE LONGVIEW CORPORATION 2004-02-24 US disclosed
WO-2000075203-A1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEMICAL COMPANY (US) 2000-12-14 WO disclosed
WO-2000052068-A1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEMICAL COMPANY (US) 2000-09-08 WO disclosed
US-6066702-A AN ALPHA-OLEFIN IS POLYMERIZED OR COPOLYMERIZED USING, AS EXTERNAL ELECTRON DONORS, THREE KINDS OF ORGANOSILICON COMPOUNDS, A SOLID COMPLEX TITANUM HALIDE, MAGESIUM COMPOUND, AN INTERNAL ELECTRON DONOR AND AN ORGANOMETALLIC COMPOUND SAMSUNG GENERAL CHEMICALS CO., LTD. (CN) 2000-05-23 US disclosed
US-5948872-A CONTAINING MAGNESIUM, HALOGEN, TITANIUM AND A COMPOUND HAVING AT LEAST TWO ETHER LINKAGS WITH A PLURALITY OF INTERMEDIATELY EXISTING BONDING ATOMS MITSUI CHEMICALS, INC. (JP) 1999-09-07 US disclosed
US-5726262-A RESULTING IN POLYMERS HIGH IN STEREOSPECIFICITY MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-03-10 US disclosed
EP-0452156-B1 Solid titanium catalyst component for olefin polymerization, olefin polymerization catalyst, prepolymerized polyolefin-containing catalyst and method of olefin polymerization MITSUI PETROCHEMICAL IND (JP) 1997-08-13 EP disclosed
EP-0542243-B1 Thermal disproportionation of organooxysilanes DOW CORNING (US) 1997-06-18 EP disclosed
EP-0542243-A1 Thermal disproportionation of organooxysilanes DOW CORNING CORPORATION (US) 1993-05-19 EP disclosed
US-5126472-A Phenyldialkoxysilanes to diphenyldialkoxysilanes and cycloalkyldialkoxysilanes to dicyclodialkoxysilanes DOW CORNING CORPORATION (US) 1992-06-30 US disclosed
EP-0452156-A2 Solid titanium catalyst component for olefin polymerization, olefin polymerization catalyst, prepolymerized polyolefin-containing catalyst and method of olefin polymerization MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-10-16 EP disclosed