Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.33 |
| ▸ | CTSS | P25774 | 3/20 | 0.33 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4768808 | 0.91 | — | — | |
| SCHEMBL4762019 | 0.91 | — | — | |
| SCHEMBL6214132 | 0.91 | — | — | |
| SCHEMBL6214191 | 0.91 | — | — | |
| SCHEMBL7010659 | 0.86 | CTSK (0.34) | CTSLCTSSCTSKPTGDR2 | |
| SCHEMBL4761916 | 0.85 | PSEN1 (0.33) | CTSLCTSSCTSKPTGDR2EP300 | |
| SCHEMBL6213210 | 0.84 | — | — | |
| SCHEMBL4768878 | 0.83 | CTSL (0.31) | CTSLCTSSCTSK | |
| SCHEMBL7425879 | 0.80 | EP300 (0.33) | EP300 | |
| SCHEMBL4762955 | 0.77 | PSEN1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1320370-A4 | METHOD OF TREATMENT | SMITHKLINE BEECHAM CORP (US) | 2008-10-22 | — | — | EP | disclosed |
| EP-1320370-A1 | METHOD OF TREATMENT | SmithKline Beecham Corporation (US) | 2003-06-25 | — | — | EP | disclosed |
| WO-2002017924-A1 | METHOD OF TREATMENT | SMITHKLINE BEECHAM CORPORATION (GB) | 2002-03-07 | — | — | WO | disclosed |