SCHEMBL4770683

SCHEMBL4770683

CC(CCOC(=O)c1ccc(OCC(F)(F)F)nc1)=C(F)F

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.56
MAPT P10636 2/20 0.49
POLB P06746 1/20 0.46
MAPK1 P28482 1/20 0.46
EPHX2 P34913 4/20 0.43
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
CYP2J2 P51589 1/20 0.42
SCN9A Q15858 2/20 0.40
TRPV1 Q8NER1 1/20 0.38
DGAT1 O75907 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4771199 0.89 MAPT (0.42) L3MBTL1MAPTPOLBEPHX2
SCHEMBL4762510 0.86 MAPT (0.54) L3MBTL1MAPTPOLB
SCHEMBL4767239 0.85 MAPT (0.43) L3MBTL1MAPTMAPK1CYP2C19
SCHEMBL4771237 0.84 L3MBTL1 (0.37) L3MBTL1MAPTPOLB
SCHEMBL4763551 0.84 L3MBTL1 (0.46) L3MBTL1MAPTMAPK1CYP2C9CYP2C19
SCHEMBL4771394 0.83 LMNA (0.46) L3MBTL1MAPTMAPK1CYP2C19
SCHEMBL4767243 0.82 LMNA (0.48) L3MBTL1MAPT
SCHEMBL4770536 0.82 LMNA (0.48) L3MBTL1MAPT
SCHEMBL4763085 0.82 LMNA (0.48) L3MBTL1MAPT
SCHEMBL4763338 0.82 MAPT (0.45) L3MBTL1MAPTPOLBEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1439169-B1 DIFLUOROALKENE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE SAME, AND INTERMEDIATE THEREFOR KUMIAI CHEMICAL INDUSTRY CO (JP) 2008-08-06 EP disclosed
US-7273878-B2 Difluoroalkene derivative, pest control agent containing the same, and intermediate therefor KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2007-09-25 US disclosed
US-20040248872-A1 Difluoroalkene derivative, pest control agent containing the same, and intermediate therefor IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 2004-12-09 US disclosed
EP-1439169-A1 DIFLUOROALKENE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE SAME, AND INTERMEDIATE THEREFOR KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2004-07-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040248872-A1 Difluoroalkene derivative, pest control agent containing the same, and intermediate therefor DDT, WEE1, NOTUM L3MBTL1 17/4885MAPT 4388/4885POLB 3681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.