Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 3/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CCR1 | P32246 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4127687 | 0.91 | SMN1; SMN2 (0.49) | CTSKTRPV4DRD2DRD4CTSL | |
| SCHEMBL13872529 | 0.91 | SMN1; SMN2 (0.49) | CTSKTRPV4DRD2DRD4CTSL | |
| SCHEMBL4133648 | 0.82 | CTSL (0.48) | CTSKTRPV4CTSLCTSSCCR1 | |
| SCHEMBL13872567 | 0.82 | CTSL (0.48) | CTSKTRPV4CTSLCTSSCCR1 | |
| SCHEMBL4142303 | 0.77 | CAPN1 (0.48) | CTSKTRPV4CTSLCTSSCCR1 | |
| SCHEMBL4139657 | 0.75 | CAPN1 (0.51) | CTSKTRPV4CTSLCTSSCCR1 | |
| SCHEMBL4136044 | 0.74 | TRPV4 (0.52) | CTSKTRPV4CTSLCTSSCCR1 | |
| SCHEMBL4135455 | 0.74 | TRPV4 (0.50) | CTSKTRPV4CTSLCAPN1ALDH1A1 | |
| SCHEMBL4131282 | 0.74 | TRPV4 (0.44) | TRPV4CTSLCCR1CAPN1ALDH1A1 | |
| SCHEMBL4147709 | 0.74 | TRPV4 (0.44) | TRPV4CTSLCTSSCCR1CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940785-A2 | ACYCLIC 1,4-DIAMINES AND USES THEREOF | SmithKline Beecham Corporation (US) | 2008-07-09 | — | — | EP | claimed |
| WO-2007030761-A2 | ACYCLIC 1,4-DIAMINES AND USES THEREOF | SMITHKLINE BEECHAM CORPORATION (US) | 2007-03-15 | — | — | WO | claimed |