Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 14/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 14/20 | 0.51 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 5/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4770834 | 1.00 | TAS1R3 (0.51) | TAS1R3TAS1R1BCAT1CTSKCTSL | |
| SCHEMBL4761901 | 0.95 | TAS1R3 (0.48) | TAS1R3TAS1R1BCAT1CTSKCTSL | |
| SCHEMBL4761899 | 0.95 | TAS1R3 (0.48) | TAS1R3TAS1R1BCAT1CTSKCTSL | |
| SCHEMBL4762061 | 0.95 | TAS1R3 (0.47) | TAS1R3TAS1R1CTSKCTSLCTSB | |
| SCHEMBL4762063 | 0.95 | TAS1R3 (0.47) | TAS1R3TAS1R1CTSKCTSLCTSB | |
| SCHEMBL6586348 | 0.94 | TAS1R3 (0.43) | TAS1R3TAS1R1CTSKCTSLCTSB | |
| SCHEMBL6586343 | 0.94 | TAS1R3 (0.43) | TAS1R3TAS1R1CTSKCTSLCTSB | |
| SCHEMBL4769990 | 0.91 | TAS1R3 (0.50) | TAS1R3TAS1R1CTSKCTSLCTSS | |
| SCHEMBL4765650 | 0.91 | TAS1R3 (0.50) | TAS1R3TAS1R1CTSKCTSLCTSS | |
| SCHEMBL4767072 | 0.90 | TAS1R3 (0.38) | TAS1R3TAS1R1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1320370-A4 | METHOD OF TREATMENT | SMITHKLINE BEECHAM CORP (US) | 2008-10-22 | — | — | EP | disclosed |
| EP-1307204-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-06-02 | — | — | EP | disclosed |
| EP-1320370-A1 | METHOD OF TREATMENT | SmithKline Beecham Corporation (US) | 2003-06-25 | — | — | EP | disclosed |
| EP-1307204-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002017924-A1 | METHOD OF TREATMENT | SMITHKLINE BEECHAM CORPORATION (GB) | 2002-03-07 | — | — | WO | disclosed |
| WO-2001095911-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-12-20 | — | — | WO | disclosed |