Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 11/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 11/20 | 0.43 |
| ▸ | CTSK | P43235 | 7/20 | 0.36 |
| ▸ | CTSL | P07711 | 6/20 | 0.35 |
| ▸ | CTSS | P25774 | 5/20 | 0.35 |
| ▸ | CTSB | P07858 | 3/20 | 0.35 |
| ▸ | CTSV | O60911 | 2/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6586348 | 1.00 | TAS1R3 (0.43) | TAS1R3TAS1R1CTSKCTSLCTSS | |
| SCHEMBL4770834 | 0.94 | TAS1R3 (0.51) | TAS1R3TAS1R1CTSKCTSLCTSS | |
| SCHEMBL4770836 | 0.94 | TAS1R3 (0.51) | TAS1R3TAS1R1CTSKCTSLCTSS | |
| SCHEMBL6590536 | 0.93 | TAS1R3 (0.38) | TAS1R3TAS1R1CTSKCTSLCTSS | |
| SCHEMBL6590533 | 0.93 | TAS1R3 (0.38) | TAS1R3TAS1R1CTSKCTSLCTSS | |
| SCHEMBL4762061 | 0.93 | TAS1R3 (0.47) | TAS1R3TAS1R1CTSKCTSLCTSS | |
| SCHEMBL4762063 | 0.93 | TAS1R3 (0.47) | TAS1R3TAS1R1CTSKCTSLCTSS | |
| SCHEMBL4767072 | 0.92 | TAS1R3 (0.38) | TAS1R3TAS1R1CTSK | |
| SCHEMBL4767079 | 0.92 | TAS1R3 (0.38) | TAS1R3TAS1R1CTSK | |
| SCHEMBL6590283 | 0.89 | TAS1R3 (0.39) | TAS1R3TAS1R1CTSKCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307204-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-06-02 | — | — | EP | disclosed |
| EP-1307204-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2001095911-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-12-20 | — | — | WO | disclosed |