SCHEMBL4770840

SCHEMBL4770840

NC(C=O)(C(=O)O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.47
CYP2D6 P10635 1/20 0.47
KCNN4 O15554 5/20 0.42
MAPT P10636 1/20 0.42
KMT2A Q03164 1/20 0.42
ALDH1A1 P00352 2/20 0.41
TSHR P16473 1/20 0.41
HIF1A Q16665 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 2/20 0.40
HTT P42858 1/20 0.39
NPSR1 Q6W5P4 1/20 0.37
MAPK1 P28482 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28220779 0.81 CYP1A2 (0.41) CYP1A2CYP2D6KCNN4MAPTKMT2A
SCHEMBL27348188 0.78 CYP1A2 (0.43) CYP1A2CYP2D6KCNN4MAPTKMT2A
SCHEMBL3824269 0.78 CYP1A2 (0.47) CYP1A2CYP2D6KCNN4MAPTKMT2A
SCHEMBL28901733 0.77 CYP1A2 (0.48) CYP1A2CYP2D6KCNN4MAPTKMT2A
Water SCHEMBL28284372 0.76 CYP1A2 (0.42) CYP1A2CYP2D6KCNN4MAPTKMT2A
SCHEMBL22164590 0.76 CYP1A2 (0.42) CYP1A2CYP2D6KCNN4MAPTKMT2A
SCHEMBL28036734 0.75 PIN1 (0.47) KCNN4MAPTKMT2AALDH1A1TSHR
SCHEMBL548166 0.73 CYP1A2 (0.54) CYP1A2CYP2D6KCNN4MAPTKMT2A
SCHEMBL1814746 0.73 KCNN4 (0.46) CYP1A2CYP2D6KCNN4MAPTKMT2A
SCHEMBL11043920 0.72 HTT (0.46) CYP1A2CYP2D6KCNN4MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115974304-A Treatment device and treatment method for sodium bromide wastewater in photoinitiator production process 山东久日化学科技有限公司 2023-04-18 CN disclosed
CN-115893746-A Method for treating sodium bromide wastewater in photoinitiator production process 山东久日化学科技有限公司 2023-04-04 CN disclosed
CN-109970759-A The inhibitor of protein tyrosine kinase activity 梅特希尔基因公司 2019-07-05 CN disclosed
CN-105777776-A Inhibitors Of Protein Tyrosine Kinase Activity 梅特希尔基因公司 2016-07-20 CN disclosed
EP-1924551-A2 ORGANIC COMPOUNDS Novartis Pharma AG (CH) 2008-05-28 EP disclosed
WO-2007025709-A2 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2007-03-08 WO disclosed