Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.39 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9664112 | 0.95 | FAAH (0.59) | FAAHMEN1MAPK1KMT2ADNM1 | |
| SCHEMBL18556703 | 0.95 | FAAH (0.59) | FAAHMEN1MAPK1KMT2ADNM1 | |
| SCHEMBL9664111 | 0.93 | FAAH (0.62) | FAAHMEN1MAPK1KMT2ADNM1 | |
| SCHEMBL9666504 | 0.93 | FAAH (0.62) | FAAHMEN1MAPK1KMT2ADNM1 | |
| SCHEMBL9664778 | 0.93 | FAAH (0.62) | FAAHMEN1MAPK1KMT2ADNM1 | |
| SCHEMBL19933125 | 0.93 | FAAH (0.62) | FAAHMEN1MAPK1KMT2ADNM1 | |
| SCHEMBL9666920 | 0.93 | FAAH (0.62) | FAAHMEN1MAPK1KMT2ADNM1 | |
| SCHEMBL9665948 | 0.93 | FAAH (0.62) | FAAHMEN1MAPK1KMT2ADNM1 | |
| SCHEMBL21587883 | 0.93 | FAAH (0.62) | FAAHMEN1MAPK1KMT2ADNM1 | |
| SCHEMBL13075715 | 0.89 | CTSD (0.45) | FAAHMEN1MAPK1KMT2ADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2002837-A1 | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-12-17 | — | — | EP | disclosed |
| EP-1741713-A2 | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists | Bristol-Myers Squibb Company (US) | 2007-01-10 | — | — | EP | disclosed |