Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.37 |
| ▸ | PARL | Q9H300 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3447228 | 0.97 | PSIP1 (0.40) | PSIP1HSD11B1PARLPOLBSMN1; SMN2 | |
| SCHEMBL476998 | 0.92 | PSIP1 (0.47) | PSIP1HSD11B1PARLPOLBSMN1; SMN2 | |
| SCHEMBL3446801 | 0.90 | PARL (0.41) | PSIP1HSD11B1PARLPOLBSMN1; SMN2 | |
| SCHEMBL1954965 | 0.90 | PARL (0.41) | PSIP1HSD11B1PARLPOLBSMN1; SMN2 | |
| SCHEMBL3448669 | 0.90 | PARL (0.41) | PSIP1HSD11B1PARLPOLBSMN1; SMN2 | |
| SCHEMBL11081117 | 0.86 | PARL (0.36) | PSIP1HSD11B1PARLPOLBSMN1; SMN2 | |
| SCHEMBL3447950 | 0.86 | STAT3 (0.41) | CYP2C19ALDH1A1MEN1KMT2A | |
| SCHEMBL5109012 | 0.84 | TSHR (0.52) | HSD11B1PARLCYP2C19POLBSMN1; SMN2 | |
| SCHEMBL3447390 | 0.83 | STAT3 (0.41) | CYP2C19ALDH1A1MEN1KMT2A | |
| SCHEMBL2058282 | 0.82 | PARL (0.46) | PSIP1HSD11B1PARLSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3807339-A1 | TRANSESTERIFICATION METHOD FOR SIMULTANEOUSLY PRODUCING AT LEAST TWO DIFFERENT POLYCARBONATES IN A PRODUCTION FACILITY | Covestro Intellectual Property GmbH & Co. KG (DE) | 2021-04-21 | — | — | EP | disclosed |
| WO-2019238419-A1 | TRANSESTERIFICATION METHOD FOR SIMULTANEOUSLY PRODUCING AT LEAST TWO DIFFERENT POLYCARBONATES IN A PRODUCTION FACILITY | COVESTRO DEUTSCHLAND AG (DE) | 2019-12-19 | — | — | WO | disclosed |
| EP-2147038-B1 | METHOD FOR THE PRODUCTION OF POLYCARBONATE ACCORDING TO A MELT TRANSESTERIFICATION PROCESS | BAYER IP GMBH (DE) | 2015-07-01 | — | — | EP | disclosed |
| EP-2058363-B1 | Method of manufacturing polycarbonate using the melting ester interchange method | BAYER MATERIALSCIENCE AG (DE) | 2012-02-01 | — | — | EP | disclosed |
| US-7814626-B2 | Process for the preparation of polycarbonate by the melt transesterification process | BAYER MATERIALSCIENCE AG (DE) | 2010-10-19 | — | — | US | disclosed |
| EP-2147038-A2 | METHOD FOR THE PRODUCTION OF POLYCARBONATE ACCORDING TO A MELT TRANSESTERIFICATION PROCESS | Bayer MaterialScience AG (DE) | 2010-01-27 | — | — | EP | disclosed |
| EP-2058363-A1 | Method of manufacturing polycarbonate using the melting ester interchange method | Bayer MaterialScience AG (DE) | 2009-05-13 | — | — | EP | disclosed |
| US-20090117314-A1 | PROCESS FOR THE PREPARATION OF POLYCARBONATE BY THE MELT TRANSESTERIFICATION METHOD | BAYER MATERIALSCIENCE AG (DE) | 2009-05-07 | — | — | US | disclosed |
| US-20080319156-A1 | Process For The Preparation Of Polycarbonate By The Melt Transesterification Process | BAYER MATERIALSCIENCE AG (DE) | 2008-12-25 | — | — | US | disclosed |
| WO-2008138517-A2 | METHOD FOR THE PRODUCTION OF POLYCARBONATE ACCORDING TO A MELT TRANSESTERIFICATION PROCESS | BAYER MATERIALSCIENCE AG (DE) | 2008-11-20 | — | — | WO | disclosed |