Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GPR6 | P46095 | 1/20 | 0.40 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4765179 | 0.97 | SLC2A1 (0.44) | NR1H4MALT1MAPTHRH3TP53 | |
| SCHEMBL4765960 | 0.91 | NR1H4 (0.52) | NR1H4MALT1MAPTHRH3SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4770084 | 0.91 | NR1H4 (0.51) | NR1H4MALT1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL4765305 | 0.87 | RAB9A (0.48) | HRH3SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4774495 | 0.86 | RAB9A (0.47) | HRH3SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL4765164 | 0.84 | MAPT (0.49) | MAPTHRH3TP53THRBSMN1; SMN2 | |
| SCHEMBL4765384 | 0.83 | MAPT (0.50) | MAPTHRH3TP53THRBSMN1; SMN2 | |
| SCHEMBL4768108 | 0.80 | NPC1 (0.51) | MAPTHRH3TP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4776625 | 0.79 | NPC1 (0.50) | MAPTHRH3TP53SMN1; SMN2 | |
| SCHEMBL4774462 | 0.78 | RAB9A (0.59) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | claimed |