Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4773493 | 0.93 | ADRB2 (0.57) | ADRB2 | |
| SCHEMBL4775882 | 0.87 | ADRB2 (0.60) | ADRB2 | |
| SCHEMBL3623719 | 0.84 | ADRB2 (0.60) | ADRB2 | |
| SCHEMBL3588405 | 0.82 | ADRB2 (0.64) | ADRB2 | |
| SCHEMBL3589910 | 0.81 | ADRB2 (0.80) | ADRB2 | |
| SCHEMBL4771293 | 0.80 | ADRB2 (0.66) | ADRB2 | |
| SCHEMBL3623716 | 0.79 | ADRB2 (0.64) | ADRB2 | |
| SCHEMBL4773485 | 0.79 | ADRB2 (0.58) | ADRB2 | |
| Trifluoroacetic Acid SCHEMBL3582500 | 0.77 | ADRB2 (0.73) | ADRB2 | |
| SCHEMBL3622886 | 0.77 | ADRB2 (0.62) | ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915354-A1 | NOVEL BENZOTHIAZOLONE DERIVATIVES | AstraZeneca AB (SE) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007018461-A1 | NOVEL BENZOTHIAZOLONE DERIVATIVES | ASTRAZENECA AB (SE) | 2007-02-15 | — | — | WO | disclosed |