Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4773493 | 0.89 | ADRB2 (0.57) | ADRB2 | |
| SCHEMBL4771290 | 0.87 | ADRB2 (0.56) | ADRB2 | |
| SCHEMBL3601528 | 0.84 | ADRB2 (0.62) | ADRB2 | |
| SCHEMBL3583833 | 0.81 | ADRB2 (0.68) | ADRB2 | |
| SCHEMBL3586438 | 0.80 | ADRB2 (0.83) | ADRB2 | |
| Bromide SCHEMBL3589861 | 0.80 | ADRB2 (0.82) | ADRB2 | |
| SCHEMBL4775886 | 0.79 | ADRB2 (0.69) | ADRB2 | |
| SCHEMBL3611658 | 0.78 | ADRB2 (0.66) | ADRB2 | |
| SCHEMBL3623194 | 0.77 | ADRB2 (0.66) | ADRB2 | |
| SCHEMBL4218384 | 0.75 | ADRB2 (1.00) | ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915354-A1 | NOVEL BENZOTHIAZOLONE DERIVATIVES | AstraZeneca AB (SE) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007018461-A1 | NOVEL BENZOTHIAZOLONE DERIVATIVES | ASTRAZENECA AB (SE) | 2007-02-15 | — | — | WO | disclosed |