Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5276342 | 1.00 | RAB9A (0.46) | RAB9AP4HTMALOX5PIM2KDM4E | |
| SCHEMBL15653009 | 0.81 | — | — | |
| SCHEMBL6219602 | 0.80 | RAB9A (0.45) | RAB9AP4HTMALOX5PIM2KDM4E | |
| Hydrochloric Acid SCHEMBL5275271 | 0.78 | RAB9A (0.44) | RAB9AP4HTMALOX5PIM2KDM4E | |
| SCHEMBL4778419 | 0.76 | RAB9A (0.42) | RAB9AP4HTMALOX5KDM4EALDH1A1 | |
| SCHEMBL5275224 | 0.76 | RAB9A (0.42) | RAB9AP4HTMALOX5KDM4EALDH1A1 | |
| SCHEMBL3888548 | 0.76 | ALDH1A1 (0.44) | RAB9AP4HTMALOX5KDM4EALDH1A1 | |
| SCHEMBL3888550 | 0.76 | ALDH1A1 (0.44) | RAB9AP4HTMALOX5KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL4777307 | 0.70 | RAB9A (0.41) | RAB9AP4HTMALOX5KDM4EALDH1A1 | |
| SCHEMBL21002093 | 0.70 | KDM4E (0.59) | RAB9AP4HTMKDM4EHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973902-A2 | 3-HETEROCYCLYLACRYLAMIDE COMPOUNDS AS FABI INHIBITORS AND ANTIBACTERIAL AGENTS | Affinium Pharmaceuticals, Inc. (CA) | 2008-10-01 | — | — | EP | disclosed |
| EP-1828167-A2 | ACRYLAMIDE DERIVATIVES AS ANTIBIOTIC AGENTS | Affinium Pharmaceuticals, Inc. (CA) | 2007-09-05 | — | — | EP | disclosed |
| WO-2007067416-A2 | HETEROCYCLYLACRYLAMIDE COMPOUNDS AS FABI INHIBITORS AND ANTIBACTERIAL AGENTS | AFFINIUM PHARMACEUTICALS, INC. (CA) | 2007-06-14 | — | — | WO | disclosed |
| WO-2007053131-A2 | ACRYLAMIDE DERIVATIVES AS ANTIBIOTIC AGENTS | AFFINIUM PHARMACEUTICALS, INC. (CA) | 2007-05-10 | — | — | WO | disclosed |