Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 4/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.45 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2568446 | 0.83 | TP53 (0.47) | HTTNR4A3TP53ALOX12SMN1; SMN2 | |
| SCHEMBL3873874 | 0.83 | HTT (0.63) | HTTNR4A3TP53ALOX12ALDH1A1 | |
| SCHEMBL2220486 | 0.81 | HTT (0.56) | HTTTP53ALOX12ALDH1A1NPC1 | |
| SCHEMBL2217305 | 0.81 | HTT (0.46) | HTTNR4A3TP53ALOX12ALDH1A1 | |
| SCHEMBL4771303 | 0.78 | HTT (1.00) | HTTTP53ALOX12ALDH1A1MAPK1 | |
| SCHEMBL2218503 | 0.78 | HTT (0.56) | HTTTP53ALOX12ALDH1A1NPC1 | |
| SCHEMBL2219018 | 0.78 | HTT (0.52) | HTTTP53ALOX12ALDH1A1NPC1 | |
| SCHEMBL17324731 | 0.77 | HTT (0.51) | HTTNR4A3TP53ALOX12ALDH1A1 | |
| SCHEMBL4789300 | 0.75 | TP53 (0.69) | HTTTP53ALOX12NPC1RAB9A | |
| SCHEMBL4770852 | 0.74 | GPBAR1 (0.61) | HTTNR4A3TP53ALOX12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109666158-B | Hybrid dynamic polymer and application thereof | 厦门逍扬运动科技有限公司 | 2023-04-07 | — | — | CN | disclosed |
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | disclosed |