Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8837510 | 0.85 | TRPM8 (0.40) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL9641174 | 0.83 | TRPM8 (0.41) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL28635187 | 0.80 | — | — | |
| SCHEMBL1380265 | 0.80 | TRPM8 (0.41) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL13733054 | 0.79 | TRPM8 (0.50) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL2761888 | 0.79 | TRPM8 (0.50) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL1983430 | 0.76 | TRPM8 (0.52) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL4305614 | 0.76 | TRPM8 (0.47) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL5358187 | 0.75 | TRPM8 (0.43) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL24540327 | 0.75 | TRPM8 (0.50) | TRPM8TRPA1EPHX1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1353653-A4 | CHEWING GUMS AND RELATED PRODUCTS THAT PROVIDE BREATH FRESHENING CHARACTERISTICS | WRIGLEY W M JUN CO (US) | 2008-10-29 | — | — | EP | disclosed |
| EP-1353653-A1 | CHEWING GUMS AND RELATED PRODUCTS THAT PROVIDE BREATH FRESHENING CHARACTERISTICS | WM. WRIGLEY JR. COMPANY (US) | 2003-10-22 | — | — | EP | disclosed |
| WO-2002051392-A1 | CHEWING GUMS AND RELATED PRODUCTS THAT PROVIDE BREATH FRESHENING CHARACTERISTICS | WM. WRIGLEY JR. COMPANY (US) | 2002-07-04 | — | — | WO | disclosed |