Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4772063 | 0.85 | TRPM8 (0.46) | TRPM8TRPA1EPHX1ALDH1A1KDM4E | |
| SCHEMBL9641174 | 0.83 | TRPM8 (0.41) | TRPM8TRPA1EPHX1ALDH1A1KDM4E | |
| SCHEMBL5358187 | 0.78 | TRPM8 (0.43) | TRPM8TRPA1EPHX1ALDH1A1KDM4E | |
| SCHEMBL1380265 | 0.73 | TRPM8 (0.41) | TRPM8TRPA1EPHX1ALDH1A1KDM4E | |
| SCHEMBL2761888 | 0.72 | TRPM8 (0.50) | TRPM8TRPA1EPHX1ALDH1A1KDM4E | |
| SCHEMBL13733054 | 0.72 | TRPM8 (0.50) | TRPM8TRPA1EPHX1ALDH1A1KDM4E | |
| SCHEMBL1983430 | 0.70 | TRPM8 (0.52) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 | |
| SCHEMBL4305614 | 0.69 | TRPM8 (0.47) | TRPM8TRPA1EPHX1ALDH1A1KDM4E | |
| SCHEMBL24540327 | 0.69 | TRPM8 (0.50) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 | |
| SCHEMBL19189292 | 0.69 | TRPM8 (0.50) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688733-A | TRANSITION METAL-IMIDOARYL AMINE COMPLEX | DSM N.V. (NL) | 1997-11-18 | — | — | US | disclosed |