Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20892703 | 0.79 | ALDH1A1 (0.36) | ALDH1A1CYP2D6CA12CA1CA2 | |
| SCHEMBL20892747 | 0.79 | ALDH1A1 (0.36) | ALDH1A1CYP2D6CA12CA1CA2 | |
| SCHEMBL31694248 | 0.78 | ALDH1A1 (0.42) | ALDH1A1CYP2D6CA12CA1CA2 | |
| SCHEMBL28926138 | 0.78 | CA12 (0.42) | ALDH1A1CYP2D6CA12CA1CA2 | |
| SCHEMBL1524492 | 0.78 | ALDH1A1 (0.38) | ALDH1A1CYP2D6CA12CA1CA2 | |
| SCHEMBL20892679 | 0.78 | MEN1 (0.36) | ALDH1A1CYP2D6CA12CA1CA2 | |
| SCHEMBL23964502 | 0.76 | MEN1 (0.38) | ALDH1A1CYP2D6CA12CA1CA2 | |
| SCHEMBL20892694 | 0.76 | ALDH1A1 (0.34) | ALDH1A1CYP2D6CA12CA1CA2 | |
| SCHEMBL20892748 | 0.76 | MEN1 (0.35) | ALDH1A1CYP2D6CA12CA1CA2 | |
| SCHEMBL1270954 | 0.76 | ALDH1A1 (0.46) | ALDH1A1CYP2D6HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220313564-A1 | DENTAL RESTORATION COMPOSITE RESIN | GC CORPORATION (JP) | 2022-10-06 | — | — | US | disclosed |
| EP-4018993-A1 | DENTAL RESTORATION COMPOSITE RESIN | GC Corporation (JP) | 2022-06-29 | — | — | EP | disclosed |
| US-20210332206-A1 | REGIOSELECTIVE C-H XANTHYLATION AS A PLATFORM TECHNOLOGY FOR POLYMER FUNCTIONALIZATION | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2021-10-28 | — | — | US | disclosed |
| US-10871595-B2 | Polymers and nanogel materials and methods for making and using the same | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2020-12-22 | — | — | US | disclosed |
| US-20200049858-A1 | POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE (US) | 2020-02-13 | — | — | US | disclosed |
| WO-2019070889-A1 | REGIOSELECTIVE C-H XANTHYLATION AS A PLATFORM TECHNOLOGY FOR POLYMER FUNCTIONALIZATION | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2019-04-11 | — | — | WO | disclosed |
| US-20180044518-A1 | NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE (US) | 2018-02-15 | — | — | US | disclosed |
| US-9815979-B2 | Non-reactive, hydrophilic polymers having terminal siloxanes and methods for making and using the same | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2017-11-14 | — | — | US | disclosed |
| US-20170051145-A1 | NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE (US) | 2017-02-23 | — | — | US | disclosed |
| US-9522980-B2 | Non-reactive, hydrophilic polymers having terminal siloxanes and methods for making and using the same | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2016-12-20 | — | — | US | disclosed |
| US-20110275734-A1 | NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE, INC. | 2011-11-10 | — | — | US | disclosed |
| EP-1688445-B1 | Surface chemistry modified latex and resdispersible powders, production and use thereof | RHODIA CHIMIE SA (FR) | 2010-03-31 | — | — | EP | disclosed |
| EP-1688445-A1 | Surface chemistry modified latex and resdispersible powders, production and use thereof | RHODIA CHIMIE (FR) | 2006-08-09 | — | — | EP | disclosed |
| EP-1242492-B1 | SURFACE CHEMISTRY MODIFIED LATEX AND RESDISPERSIBLE POWDERS, PRODUCTION AND USE THEREOF | RHODIA CHIMIE SA (FR) | 2006-05-17 | — | — | EP | disclosed |
| US-7012114-B2 | Surface chemistry modified latex and redispersible powders, production and use thereof | RHODIA CHIMIE (FR) | 2006-03-14 | — | — | US | disclosed |
| US-20030114548-A1 | Surface chemistry modified latex and resdispersible powders, production and use thereof | RHODIA CHIMIE (FR) | 2003-06-19 | — | — | US | disclosed |
| EP-1242492-A1 | SURFACE CHEMISTRY MODIFIED LATEX AND RESDISPERSIBLE POWDERS, PRODUCTION AND USE THEREOF | RHODIA CHIMIE (FR) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001042325-A1 | SURFACE CHEMISTRY MODIFIED LATEX AND RESDISPERSIBLE POWDERS, PRODUCTION AND USE THEREOF | RHODIA CHIMIE (FR) | 2001-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220313564-A1 | DENTAL RESTORATION COMPOSITE RESIN | ARCN1, COG1, SEM1 | ALDH1A1 814/4885CYP2D6 4596/4885CA12 3328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.