Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18117673 | 0.91 | MAPT (0.60) | RAB9AALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL20787721 | 0.91 | HPGD (0.59) | RAB9AALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL13299505 | 0.88 | MAPT (0.56) | RAB9AALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL12896256 | 0.88 | MAPT (0.61) | RAB9AALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL12896253 | 0.88 | MAPT (0.61) | RAB9AALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL9012074 | 0.87 | RAB9A (0.52) | RAB9AALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL12462983 | 0.87 | HPGD (0.58) | RAB9AALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL17212256 | 0.86 | HPGD (0.56) | RAB9AALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL12727778 | 0.86 | HPGD (0.56) | RAB9AALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL14160684 | 0.86 | LMNA (0.57) | RAB9AALDH1A1HPGDSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891050-A1 | NEW DERIVATIVES OF PYRROLYLTRIAZINE TOGETHER WITH METHODS FOR OBTAINING THEM AND THEIR USE AS PROTECTING AGENTS AGAINST UV RADIATION | ISDIN, S.A. (ES) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006128920-A1 | NEW DERIVATIVES OF PYRROLYLTRIAZINE TOGETHER WITH METHODS FOR OBTAINING THEM AND THEIR USE AS PROTECTING AGENTS AGAINST UV RADIATION | ISDIN, S.A. (ES) | 2006-12-07 | — | — | WO | disclosed |
| WO-2006128791-A1 | NEW DERIVATIVES OF PYRROLYLTRIAZINE TOGETHER WITH METHODS FOR OBTAINING THEM AND THEIR USE AS PROTECTING AGENTS AGAINST UV RADIATION | ISDIN, S.A. (ES) | 2006-12-07 | — | — | WO | disclosed |