Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CCR5 | P51681 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1927705 | 0.95 | ALDH1A1 (0.58) | HRH3ALDH1A1KDM4ERAB9AMEN1 | |
| SCHEMBL1241903 | 0.85 | ALDH1A1 (0.57) | ALDH1A1KDM4ERAB9AMEN1CYP2D6 | |
| SCHEMBL24008985 | 0.85 | RAB9A (0.64) | HRH3ALDH1A1RAB9AMEN1CYP2D6 | |
| SCHEMBL1239295 | 0.85 | ALDH1A1 (0.57) | ALDH1A1KDM4ERAB9AMEN1CYP2D6 | |
| SCHEMBL1239292 | 0.85 | ALDH1A1 (0.57) | ALDH1A1KDM4ERAB9AMEN1CYP2D6 | |
| SCHEMBL27569958 | 0.83 | HRH3 (0.57) | HRH3ALDH1A1KDM4ERAB9AMEN1 | |
| SCHEMBL4591942 | 0.79 | KDM4E (0.59) | HRH3ALDH1A1KDM4ECCR5SIGMAR1 | |
| SCHEMBL12642582 | 0.79 | RAB9A (0.60) | HRH3ALDH1A1KDM4ERAB9AMEN1 | |
| SCHEMBL4141085 | 0.79 | ALDH1A1 (0.60) | HRH3ALDH1A1KDM4ERAB9AMEN1 | |
| SCHEMBL24495209 | 0.78 | SPHK1 (0.63) | HRH3SIGMAR1ACHEKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902044-A1 | 5-HTX MODULATORS | Bio Medisinsk Innovasjon AS (NO) | 2008-03-26 | — | — | EP | disclosed |
| WO-2007007072-A1 | 5-HTX MODULATORS | BIO-MEDISINSK INNOVASJON AS (NO) | 2007-01-18 | — | — | WO | disclosed |