Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1866639 | 0.93 | — | — | |
| SCHEMBL1867136 | 0.72 | — | — | |
| SCHEMBL16569238 | 0.71 | — | — | |
| SCHEMBL16569236 | 0.71 | — | — | |
| SCHEMBL1866961 | 0.69 | LMNA (0.37) | LMNAMAPT | |
| SCHEMBL6590413 | 0.68 | — | — | |
| SCHEMBL14974379 | 0.67 | — | — | |
| SCHEMBL14975554 | 0.67 | — | — | |
| SCHEMBL266059 | 0.67 | — | — | |
| SCHEMBL10436031 | 0.67 | SHBG (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101384604-B | Ethanol or ethylene glycol cyclohexyl antibiotic derivatives | ACTELION PHARMACEUTICALS LTD | 2012-08-08 | — | — | CN | disclosed |
| CN-101384604-A | Ethanol or ethylene glycol cyclohexyl antibiotic derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2009-03-11 | — | — | CN | disclosed |
| EP-1987040-A1 | ETHANOL OR 1,2-ETHANEDIOL CYCLOHEXYL ANTIBIOTIC DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007093963-A1 | ETHANOL OR 1,2-ETHANEDIOL CYCLOHEXYL ANTIBIOTIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2007-08-23 | — | — | WO | disclosed |