Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | EBP | Q15125 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL952632 | 0.81 | LMNA (0.42) | LMNARECQLKMT2AUSP2EBP | |
| SCHEMBL952634 | 0.81 | LMNA (0.42) | LMNARECQLKMT2AUSP2EBP | |
| SCHEMBL956190 | 0.73 | LMNA (0.39) | LMNAEBPSIGMAR1 | |
| SCHEMBL956191 | 0.73 | LMNA (0.39) | LMNAEBPSIGMAR1 | |
| SCHEMBL953297 | 0.71 | SIGMAR1 (0.40) | LMNAKMT2AUSP2KDM4EEBP | |
| SCHEMBL953298 | 0.71 | SIGMAR1 (0.40) | LMNAKMT2AUSP2KDM4EEBP | |
| SCHEMBL951476 | 0.69 | SIGMAR1 (0.42) | LMNAKMT2AKDM4EEBPSIGMAR1 | |
| SCHEMBL951475 | 0.69 | SIGMAR1 (0.42) | LMNAKMT2AKDM4EEBPSIGMAR1 | |
| SCHEMBL952457 | 0.68 | LMNA (0.48) | LMNAKMT2AEBPSIGMAR1ALDH1A1 | |
| SCHEMBL952455 | 0.68 | LMNA (0.48) | LMNAKMT2AEBPSIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1755396-A1 | PIPERAZIN DERIVATIVES AND THEIR USE IN CONTROLLING PESTS | Syngeta Participations AG (CH) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005115146-A1 | PIPERAZIN DERIVATIVES AND THEIR USE IN CONTROLLING PESTS | SYNGENTA PARTICIPATIONS AG (CH) | 2005-12-08 | — | — | WO | disclosed |