SCHEMBL170426

SCHEMBL170426

Cc1ccc(S(=O)(=O)NC(N)=O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.59
CA2 P00918 2/20 0.59
MMP1 P03956 1/20 0.59
MMP2 P08253 1/20 0.59
MMP9 P14780 1/20 0.59
MMP8 P22894 1/20 0.59
MMP13 P45452 1/20 0.59
F2 P00734 1/20 0.58
PRSS1 P07477 1/20 0.58
PRSS2 P07478 1/20 0.58
PRSS3 P35030 1/20 0.58
CA12 O43570 1/20 0.57
CA4 P22748 1/20 0.57
CA6 P23280 1/20 0.57
CA5A P35218 1/20 0.57
CA7 P43166 1/20 0.57
CA9 Q16790 1/20 0.57
CA13 Q8N1Q1 1/20 0.57
CA14 Q9ULX7 1/20 0.57
LMNA P02545 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL961107 0.91 CA1 (0.50) CA1CA2MMP1MMP2MMP9
Diphenylmethane SCHEMBL28246450 0.86 GAA (0.56) CA1CA2CA12CA9LMNA
Diphenylmethane SCHEMBL28203432 0.86 GAA (0.56) CA1CA2CA12CA9LMNA
SCHEMBL29135554 0.85 LMNA (0.58) CA1CA2MMP1MMP2MMP9
SCHEMBL692083 0.83 LMNA (0.64) CA1CA2MMP1MMP2MMP9
SCHEMBL30716976 0.83 LMNA (0.66) CA1CA2MMP1MMP2MMP9
SCHEMBL5184740 0.83 LMNA (0.69) CA1CA2MMP1MMP2MMP9
SCHEMBL7363066 0.82 ALDH1A1 (0.60) CA1CA2MMP1MMP2MMP9
SCHEMBL8038636 0.82 CA1 (0.57) CA1CA2MMP1MMP2MMP9
SCHEMBL3415853 0.82 CA1 (0.57) CA1CA2MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 287 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4253075-B1 N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME SANKO CO LTD (JP) 2025-10-15 EP claimed
CN-119841748-B Preparation method of p-toluenesulfonyl urea 济南大学 2025-06-10 CN claimed
CN-120059262-A Material for thermal printing wrist strap and preparation method thereof 中裕(惠州)科技有限公司 2025-05-30 CN claimed
CN-119841748-A Preparation method of p-toluenesulfonyl urea 济南大学 2025-04-18 CN claimed
CN-119745799-A Ultrasonic activated liposome for regulating ATP-ADO axis to release immunosuppression and application thereof 浙江大学 2025-04-04 CN claimed
CN-119709939-A Method for detecting xanthine oxidase inhibition effect of reagent and application thereof 瑞德肝脏疾病研究(上海)有限公司 2025-03-28 CN claimed
CN-117990836-A Method for analyzing concentration SOMCL668 in plasma by liquid chromatography-tandem mass spectrometry 苏州熙萃医药科技有限公司 2024-05-07 CN claimed
CN-117466888-A Preparation method of 1H-imidazo [4,5-C ] pyridine compound 西北农林科技大学 2024-01-30 CN claimed
US-11840530-B2 Selective EP4 receptor antagonistic substance for treatment of cancer ASKAT INC. (JP) 2023-12-12 US claimed
CN-117187810-A Microetching roughening solution for high-frequency high-speed circuit board and application thereof 上海天承化学有限公司 2023-12-08 CN claimed
CN-106633166-A Foaming agent for plastic 徐勤凤 2017-05-10 CN claimed
CN-102964280-B Preparation method of toluenesulfonylurea GUANGDONG EASHU PHARMACEUTICAL CO LTD 2014-07-16 CN claimed
CN-103508934-A Preparation method of gliclazide WEIHAI WEITAI PHARMACEUTICAL TECHNOLOGY DEV CO LTD 2014-01-15 CN claimed
CN-102964280-A Preparation method of toluenesulfonylurea GUANGDONG EASHU PHARMACEUTICAL CO LTD 2013-03-13 CN claimed
CN-102557997-A Preparation method of p-toluenesulfonylurea JINAN IFT SCIENCE & TECHNOLOGY CO LTD 2012-07-11 CN claimed
CN-102219718-A New synthesis method for p-tolunesulfonyl carbamide JUYE JINLING BIO TECHNOLOGY DEV CO LTD 2011-10-19 CN claimed
CN-1010666-B Method for producing thermoplastic resin sheet CONGONLEUM CORP (US) 1990-12-05 CN claimed
CN-86101786-A Produce the printable composition of embossed decorative sheets 1986-11-05 CN claimed
US-4307170-A ACID CATALYST - AZO COUPLERS PROMOTE DISCOLORATION AND BLOOM RESISTANCE JAMES RIVER GRAPHICS, INC. (US) 1981-12-22 US claimed
US-4072712-A FROM ISOCYANATES, CATALYSIS BAYER AKTIENGESELLSCHAFT (DT) 1978-02-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11840530-B2 Selective EP4 receptor antagonistic substance for treatment of cancer PTGER4, PTGER1, PTGER2 CA1 2448/4885CA2 601/4885MMP1 3191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.