Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | CENPE | Q02224 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776936 | 1.00 | CSNK2A1 (0.44) | CSNK2A1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL5569431 | 0.88 | CSNK2A1 (0.41) | CSNK2A1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL5569436 | 0.88 | CSNK2A1 (0.41) | CSNK2A1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL14417677 | 0.81 | CSNK2A1 (0.36) | CSNK2A1MEN1KMT2ALMNAS1PR1 | |
| SCHEMBL5565205 | 0.75 | P2RX3 (0.32) | CSNK2A1P2RX3 | |
| SCHEMBL5565201 | 0.75 | P2RX3 (0.32) | CSNK2A1P2RX3 | |
| SCHEMBL1293550 | 0.69 | CSNK2A1 (0.56) | CSNK2A1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL4776494 | 0.67 | CENPE (0.54) | CSNK2A1MEN1KMT2ALMNAP2RX3 | |
| SCHEMBL4776493 | 0.67 | CENPE (0.54) | CSNK2A1MEN1KMT2ALMNAP2RX3 | |
| SCHEMBL4776495 | 0.67 | CENPE (0.54) | CSNK2A1MEN1KMT2ALMNAP2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1942732-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007056143-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-18 | — | — | WO | disclosed |