SCHEMBL477359

SCHEMBL477359

CCO[Si](CNC(=O)OC)(OCC)OCC

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.41
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3401501 0.85 GAA (0.39) MGAMGAASIMGAM2TSHR
SCHEMBL477439 0.81 EPHX1 (0.39) EPHX1MGAMGAASIMGAM2
SCHEMBL5916829 0.81 EPHX1 (0.48) EPHX1MGAMGAASIMGAM2
SCHEMBL27541671 0.81 EPHX1 (0.39) EPHX1MGAMGAASIMGAM2
SCHEMBL15823494 0.80 GAA (0.37) MGAMGAASIMGAM2
SCHEMBL12628848 0.80 KDM4E (0.36) MGAMGAASIMGAM2TSHR
SCHEMBL141335 0.79 EPHX1 (0.40) EPHX1TSHR
SCHEMBL14725999 0.79 ACHE (0.51)
SCHEMBL729764 0.78 ALOX15 (0.36) MGAMGAASIMGAM2
SCHEMBL28148716 0.78 MEN1 (0.43) MGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301433-B2 Curable organopolysiloxane compositions WACKER CHEMIE AG (DE) 2019-05-28 US disclosed
EP-3172178-B1 CURABLE ORGANOPOLYSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2018-09-12 EP disclosed
US-20170210856-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2017-07-27 US disclosed
EP-3172178-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITIONS Wacker Chemie AG (DE) 2017-05-31 EP disclosed
EP-3150649-A1 CO-INITATOR SYSTEM FOR RESIN COMPOSITIONS Henkel AG & Co. KGaA (DE) 2017-04-05 EP disclosed
US-20160054491-A1 LIQUID COATING COMPOSITIONS OF POLYMER MATRIX RESINS WITH PHOTOCHROMIC DYES AND FILMS MADE THEREFROM E.I. DU PONT DE NEMOURS AND COMPANY 2016-02-25 US disclosed
US-9249262-B2 Curable organic polymer and method for production thereof, and curable composition containing the same KANEKA CORPORATION (JP) 2016-02-02 US disclosed
WO-2016012305-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2016-01-28 WO disclosed
US-20140097392-A1 LIQUID COATING COMPOSITIONS OF POLYMER MATRIX RESINS WITH PHOTOCHROMIC DYES AND FILMS MADE THEREFROM E I DU PONT DE NEMOURS AND COMPANY (US) 2014-04-10 US disclosed
US-8426483-B2 Metal compounds for use as initiators HENKEL AG & CO. KGAA (DE) 2013-04-23 US disclosed
EP-1902112-A1 SILANE CROSS-LINKING ADHESIVE OR SEALING COMPOUNDS, METHOD FOR PRODUCING THE SAME AND THEIR USE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-03-26 EP disclosed
WO-2007048538-A1 ?-ETHOXYSILANE-MODIFIED POLYMERS, PRODUCTION AND USE THEREOF HENKEL AG & CO. KGAA (DE) 2007-05-03 WO disclosed
WO-2006136211-A1 SILANE CROSS-LINKING ADHESIVE OR SEALING COMPOUNDS, METHOD FOR PRODUCING THE SAME AND THEIR USE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-12-28 WO disclosed
US-20060247407-A1 Polymers with urea groups and silyl groups and production and use thereof HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) 2006-11-02 US disclosed
US-7057001-B2 Polymers with urea groups and silyl groups and production and use thereof HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2006-06-06 US disclosed
US-20050260401-A1 Polymers with urea groups and silyl groups and production and use thereof HENKEL AG & CO. KGAA (DE) 2005-11-24 US disclosed
CN-1572794-A Organofunctional surface-modified metal oxides WACKER CHEMIE GMBH (DE) 2005-02-02 CN disclosed
EP-1328586-A1 POLYMERS WITH UREA GROUPS AND SILYL GROUPS AND PRODUCTION AND USE THEREOF Henkel Kommanditgesellschaft auf Aktien (DE) 2003-07-23 EP disclosed
WO-2002050020-A1 METHOD FOR PRODUCING ISOCYANATES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-06-27 WO disclosed
WO-2002034838-A1 POLYMERS WITH UREA GROUPS AND SILYL GROUPS AND PRODUCTION AND USE THEREOF HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-05-02 WO disclosed