Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL126890 | 0.90 | NFKB1 (0.33) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL8406945 | 0.87 | DNM1 (0.33) | DNM1TSHR | |
| Putrescine SCHEMBL6283577 | 0.87 | NFKB1 (0.39) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Ammonia Solution, Strong SCHEMBL23577300 | 0.87 | NFKB1 (0.32) | DNM1TSHR | |
| SCHEMBL47753 | 0.86 | DNM1 (0.42) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL10587787 | 0.86 | DNM1 (0.36) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL13038075 | 0.84 | — | — | |
| SCHEMBL13647426 | 0.83 | — | — | |
| SCHEMBL202975 | 0.82 | NFKB1 (0.39) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL6334222 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180044518-A1 | NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE (US) | 2018-02-15 | — | — | US | disclosed |
| US-9815979-B2 | Non-reactive, hydrophilic polymers having terminal siloxanes and methods for making and using the same | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2017-11-14 | — | — | US | disclosed |
| US-9617423-B2 | Macroinitiator containing hydrophobic segment | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2017-04-11 | — | — | US | disclosed |
| US-20170051145-A1 | NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE (US) | 2017-02-23 | — | — | US | disclosed |
| US-9522980-B2 | Non-reactive, hydrophilic polymers having terminal siloxanes and methods for making and using the same | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2016-12-20 | — | — | US | disclosed |
| US-20160194497-A1 | MACROINITIATOR CONTAINING HYDROPHOBIC SEGMENT | JOHNSON & JOHNSON VISION CARE (US) | 2016-07-07 | — | — | US | disclosed |
| US-9321890-B2 | Macroinitiator containing hydrophobic segment | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2016-04-26 | — | — | US | disclosed |
| US-20140296368-A1 | MACROINITIATOR CONTAINING HYDROPHOBIC SEGMENT | JOHNSON & JOHNSON VISION CARE (US) | 2014-10-02 | — | — | US | disclosed |
| US-20120283381-A1 | MACROINITIATOR CONTAINING HYDROPHOBIC SEGMENT | JOHNSON & JOHNSON VISION CARE, INC. | 2012-11-08 | — | — | US | disclosed |
| US-20110275734-A1 | NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE, INC. | 2011-11-10 | — | — | US | disclosed |