Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776141 | 0.95 | POLB (0.43) | POLBALDH1A1SMN1; SMN2GAATDP1 | |
| SCHEMBL3172845 | 0.87 | POLB (0.42) | POLBALDH1A1SMN1; SMN2GAATDP1 | |
| SCHEMBL4773797 | 0.86 | POLB (0.41) | POLBALDH1A1SMN1; SMN2GAATDP1 | |
| SCHEMBL4771569 | 0.85 | POLB (0.40) | POLBALDH1A1SMN1; SMN2GAATDP1 | |
| SCHEMBL4769171 | 0.85 | POLB (0.40) | POLBALDH1A1SMN1; SMN2GAATDP1 | |
| SCHEMBL13527456 | 0.84 | POLB (0.42) | POLBALDH1A1SMN1; SMN2GAATDP1 | |
| SCHEMBL4772531 | 0.82 | POLB (0.41) | POLBALDH1A1SMN1; SMN2GAATDP1 | |
| SCHEMBL843365 | 0.80 | TSHR (0.42) | POLBALDH1A1SMN1; SMN2TDP1MAPT | |
| SCHEMBL4777754 | 0.79 | MAPT (0.43) | POLBALDH1A1SMN1; SMN2GAATDP1 | |
| SCHEMBL4773504 | 0.79 | MAPT (0.45) | POLBALDH1A1SMN1; SMN2GAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513524-A4 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES CO (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1513524-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M Innovative Properties Company (US) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003103584-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-12-18 | — | — | WO | disclosed |